ID   ALDH_AGABI     STANDARD;      PRT;   500 AA.
AC   O74187;
DT   16-OCT-2001 (Rel. 40, Created)
DT   16-OCT-2001 (Rel. 40, Last sequence update)
DT   01-FEB-2005 (Rel. 46, Last annotation update)
DE   Aldehyde dehydrogenase (EC 1.2.1.3) (ALDDH).
GN   Name=aldA;
OS   Agaricus bisporus (Common mushroom).
OC   Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes;
OC   Agaricales; Agaricaceae; Agaricus.
OX   NCBI_TaxID=5341;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Horst H39;
RA   Schaap P.J., Mueller Y., Visser J.;
RT   "Molecular structure and spatial expression of housekeeping genes in
RT   mushrooms.";
RL   Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: An aldehyde + NAD(+) + H(2)O = an acid + NADH.
CC   -!- PATHWAY: Ethanol utilization; second step.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
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DR   EMBL; Y17825; CAA76875.1; -.
DR   HSSP; Q63639; 1BI9.
DR   InterPro; IPR002086; Aldehyde_dehydr.
DR   Pfam; PF00171; Aldedh; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
KW   NAD; Oxidoreductase.
FT   NP_BIND     246    251       NAD (ADP part) (By similarity).
FT   ACT_SITE    269    269       By similarity.
FT   ACT_SITE    303    303       By similarity.
SQ   SEQUENCE   500 AA;  54395 MW;  C4FCE58B50855925 CRC64;
     MPSIFTHQWD TPVYKGSTSI NTGLFINGEF VDGVKNTTID VVNPANGKLI TKISEATEAD
     IDIAVEAAHK AFETTWGLNC SGSKRGDMLY KLAQLMEKNI DDLSAIEALD NGKTFLWAKS
     VDLSLSISTI KHYAGWADKN FGQVIETDEK KLTYSRHEPI GVVGQIIPWN FPLLMLAWKI
     GPALATGNCI VLKPSEFTPL SALRMCALIQ EAGFPPGVVN VVTGYGSTTG QAISSHMKID
     KVAFTGSTLV GRKVMEAAAK SNLKNVTLEL GGKSPVVIFD DADLEQSVNW TAHGLFWNHG
     QACCAGTRIF VQEGIYDKFL QKFTDKIKEI KLGDPFGLGI DQGPQVSQIQ YDRIMSYIES
     GRAEGATVHV GGERHGNEGY FIQPTIFTDT TPDMKIVKEE IFGPVGAVIK FKDGKEVIKQ
     ANDSNYGLAA AVFSQDINKA IETAHAFKAG TAWVNCANTI DAGVPFGGYK QSGIGRELGE
     YALHNYTNVK AVHVNLNWKM
//