ID   G3P2_AGABI     STANDARD;      PRT;   338 AA.
AC   P32636;
DT   01-OCT-1993 (Rel. 27, Created)
DT   01-OCT-1993 (Rel. 27, Last sequence update)
DT   25-OCT-2004 (Rel. 45, Last annotation update)
DE   Glyceraldehyde-3-phosphate dehydrogenase 2 (EC 1.2.1.12) (GAPDH 2).
GN   Name=gpd2;
OS   Agaricus bisporus (Common mushroom).
OC   Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes;
OC   Agaricales; Agaricaceae; Agaricus.
OX   NCBI_TaxID=5341;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Horst U3;
RX   MEDLINE=93113715; PubMed=1473176;
RA   Harmsen M.C., Schuren F.H.J., Moukha S.M., van Zuilen C.M., Punt P.J.,
RA   Wessels J.G.H.;
RT   "Sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase
RT   genes from the basidiomycetes Schizophyllum commune, Phanerochaete
RT   chrysosporium and Agaricus bisporus.";
RL   Curr. Genet. 22:447-454(1992).
CC   -!- CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate + phosphate +
CC       NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
CC   -!- PATHWAY: Second phase of glycolysis; first step.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate
CC       dehydrogenase family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; M81728; AAA32634.1; -.
DR   PIR; S26976; S26976.
DR   HSSP; P00357; 4GPD.
DR   InterPro; IPR000173; GAP_dhdrogenase.
DR   InterPro; IPR006424; GAPDH-I.
DR   Pfam; PF02800; Gp_dh_C; 1.
DR   Pfam; PF00044; Gp_dh_N; 1.
DR   PRINTS; PR00078; G3PDHDRGNASE.
DR   TIGRFAMs; TIGR01534; GAPDH-I; 1.
DR   PROSITE; PS00071; GAPDH; 1.
KW   Glycolysis; Multigene family; NAD; Oxidoreductase.
FT   BINDING     150    150       Glyceraldehyde 3-phosphate.
FT   ACT_SITE    177    177       Activates thiol group during catalysis.
SQ   SEQUENCE   338 AA;  36570 MW;  3381DBBF73B84469 CRC64;
     MVKVGINGFG RIGRIVLRNA LQFQDIEVVA VNDPFIDLEY MAYMFKYDSV HGRFKGTVEV
     KNGSFVVDGR PMKVFAERDP AAIPWGSVGA DYVVESTGVF TTIDKASAHL KGGAKKVVIS
     APSADAPMYV CGVNLDKYNP KDTIISNASC TTNCLATLAK VIHDNFGIVE GLMTTVHATT
     ATQKTVDGPS HKDWRGGRGV GNNIIPSSTG AAKAVGKVIP SLNGKLTGLS MRVPTQDVSV
     VDLVVRLEKP ASYEQIKEVM RKAAEGEYKG IIAYTDEDVV STDFISDNNS CVFDAKAGIQ
     LSPNFVKLIA WYDNEWGYSR RVCNLLQYVA KEDAKAGI
//