ID   G3P_SCHCO      STANDARD;      PRT;   337 AA.
AC   P32638;
DT   01-OCT-1993 (Rel. 27, Created)
DT   01-OCT-1993 (Rel. 27, Last sequence update)
DT   25-OCT-2004 (Rel. 45, Last annotation update)
DE   Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH).
GN   Name=GPD;
OS   Schizophyllum commune (Bracket fungus).
OC   Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes;
OC   Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=93113715; PubMed=1473176;
RA   Harmsen M.C., Schuren F.H.J., Moukha S.M., van Zuilen C.M., Punt P.J.,
RA   Wessels J.G.H.;
RT   "Sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase
RT   genes from the basidiomycetes Schizophyllum commune, Phanerochaete
RT   chrysosporium and Agaricus bisporus.";
RL   Curr. Genet. 22:447-454(1992).
CC   -!- CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate + phosphate +
CC       NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
CC   -!- PATHWAY: Second phase of glycolysis; first step.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate
CC       dehydrogenase family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; M81724; AAA33926.1; -.
DR   PIR; S26973; S26973.
DR   HSSP; P56649; 1IHX.
DR   InterPro; IPR000173; GAP_dhdrogenase.
DR   InterPro; IPR006424; GAPDH-I.
DR   Pfam; PF02800; Gp_dh_C; 1.
DR   Pfam; PF00044; Gp_dh_N; 1.
DR   PRINTS; PR00078; G3PDHDRGNASE.
DR   TIGRFAMs; TIGR01534; GAPDH-I; 1.
DR   PROSITE; PS00071; GAPDH; 1.
KW   Glycolysis; NAD; Oxidoreductase.
FT   BINDING     151    151       Glyceraldehyde 3-phosphate.
FT   ACT_SITE    178    178       Activates thiol group during catalysis.
SQ   SEQUENCE   337 AA;  36055 MW;  CBBCB4118F8F779B CRC64;
     MAVKVGINGF GRIGRIVLRN ALQLGNIEVV AINDPFIALD YMVYMFKYDT VHGRYKGTVE
     VKDGKLVVDG HAITVFAEKN PADIKWGSAG ADYIVESTGV FTTVEKASLH LQGGAKKVVI
     SAPSADAPMF VVGVNLDKYD SKYQVISNAS CTTNCLAPLA KVIHDKYGIA EGLMTTVHAT
     TATQKTVDGP SHKDWRGGRS VNNNIIPSST GAAKAVGKVI PSLNGRLTGL AFRVPTLDVS
     VVDLVVRLEK EASYDEIVAT VKEASEGPLK GILGFTDESV VSTDFTGANE SSIFDSKAGI
     AISKSFVKLI AWYDNEWGYS RRVCDLLVYA AKQDGAL
//