ID   DHE4_AGABI     STANDARD;      PRT;   457 AA.
AC   P54387;
DT   01-OCT-1996 (Rel. 34, Created)
DT   01-OCT-1996 (Rel. 34, Last sequence update)
DT   05-JUL-2004 (Rel. 44, Last annotation update)
DE   NADP-specific glutamate dehydrogenase (EC 1.4.1.4) (NADP-GDH) (NADP-
DE   dependent glutamate dehydrogenase).
GN   Name=gdhA;
OS   Agaricus bisporus (Common mushroom).
OC   Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes;
OC   Agaricales; Agaricaceae; Agaricus.
OX   NCBI_TaxID=5341;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Horst H39;
RX   MEDLINE=96180651; PubMed=8602149; DOI=10.1007/s004380050084;
RA   Schaap P.J., Mueller Y., Baars J.J.P., Op den Camp H.J.M.,
RA   Sonnenberg A.S.M., van Griensven L.J.L.D., Visser J.;
RT   "Nucleotide sequence and expression of the gene encoding NADP+-
RT   dependent glutamate dehydrogenase (gdhA) from Agaricus bisporus.";
RL   Mol. Gen. Genet. 250:339-347(1996).
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NADP(+) = 2-oxoglutarate
CC       + NH(3) + NADPH.
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; X83393; CAA58312.1; -.
DR   PIR; S63608; S63608.
DR   HSSP; P24295; 1AUP.
DR   InterPro; IPR006095; GLFV_dehydrog.
DR   InterPro; IPR006096; GLFV_dehydrog_C.
DR   InterPro; IPR006097; GLFV_dehydrog_N.
DR   Pfam; PF00208; GLFV_dehydrog; 1.
DR   Pfam; PF02812; GLFV_dehydrog_N; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
KW   NADP; Oxidoreductase.
FT   ACT_SITE    111    111       By similarity.
SQ   SEQUENCE   457 AA;  49557 MW;  1BF0E97F67078AC4 CRC64;
     MVLPHEPEFE QALHELETSL QPFLTTNPQY KKALEIIQVP ERVLQFRVTW EDDQGKPQVN
     RGFRVQYNSA LGPYKGGLRL HPTVNLSILK FLGFEQTFKN ALTGLSMGGG KGGSDFDPKG
     KSDNEIRRFC VAFMSELFRH IGQDTDVPAG DIGTGAREIG FLFGAYRRLK NEFTGMLTGK
     GINWGGSFIR PEATGYGLIY YVEHMIAHAC PEYSLDRPST LVAISGSGNV SQFTALKVIE
     LGATVLSLSD SKGSLISEKG YTKEAIEKIA ELKLKGGALE AIVDDLGAGY TYHAGKRPWT
     LLPQVHIALP GATQNEVSQE EAEALVKAGT RIVAEGSNMG CTEEAIAIFE NSRRASRAGV
     WYAPGKASNC GGVAVSGLEM AQNSQRLAWS TQEVDAKLKS IMAECYQICY TAGSRWSGEK
     VAEGVAEGEA LPSLLSGANL AGFIKVADAM KEQGDWW
//