ID H4_AGABI STANDARD; PRT; 102 AA. AC P62793; P35058; DT 01-FEB-1994 (Rel. 28, Created) DT 01-FEB-1994 (Rel. 28, Last sequence update) DT 25-OCT-2004 (Rel. 45, Last annotation update) DE Histone H4. GN Name=hhfA; OS Agaricus bisporus (Common mushroom). OC Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes; OC Agaricales; Agaricaceae; Agaricus. OX NCBI_TaxID=5341; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Horst U1; RX MEDLINE=97111990; PubMed=8953726; RA Sonnenberg A.S.M., de Groot P.W.J., Schaap P.J., Baars J.J.P., RA Visser J., van Griensven L.J.L.D.; RT "Isolation of expressed sequence tags of Agaricus bisporus and their RT assignment to chromosomes."; RL Appl. Environ. Microbiol. 62:4542-4547(1996). CC -!- FUNCTION: Histone H4, along with histone H3, plays a central role CC in nucleosome formation. CC -!- SUBUNIT: The nucleosome is an octamer containing two molecules CC each of H2A, H2B, H3 and H4. The octamer wraps approximately 146 CC bp of DNA. CC -!- SIMILARITY: Belongs to the histone H4 family. CC -------------------------------------------------------------------------- CC This Swiss-Prot entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use as long as its content is in no way modified and this statement is not CC removed. CC -------------------------------------------------------------------------- DR EMBL; X94189; CAA63899.1; -. DR HSSP; P02304; 1KX5. DR InterPro; IPR007124; Hist_TAF. DR InterPro; IPR009072; Histone-fold. DR InterPro; IPR007125; Histone_core_D. DR InterPro; IPR001951; Histone_H4. DR Pfam; PF00125; Histone; 1. DR PRINTS; PR00623; HISTONEH4. DR PROSITE; PS00047; HISTONE_H4; 1. KW Chromosomal protein; DNA-binding; Nuclear protein; Nucleosome core. FT INIT_MET 0 0 By similarity. FT DNA_BIND 16 20 SQ SEQUENCE 102 AA; 11235 MW; 6F87ECF119F9A9B1 CRC64; SGRGKGGKGL GKGGAKRHRK ILRDNIQGIT KPAIRRLARR GGVKRISGLI YEETRGVLKI FLENVIRDSV TYTEHAKRKT VTALDVVYAL KRSGRTLYGF GA //