ID   PALY_AGABI     STANDARD;      PRT;   142 AA.
AC   Q92195;
DT   01-NOV-1997 (Rel. 35, Created)
DT   01-NOV-1997 (Rel. 35, Last sequence update)
DT   25-OCT-2004 (Rel. 45, Last annotation update)
DE   Phenylalanine ammonia-lyase (EC 4.3.1.5) (Fragment).
GN   Name=palA;
OS   Agaricus bisporus (Common mushroom).
OC   Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes;
OC   Agaricales; Agaricaceae; Agaricus.
OX   NCBI_TaxID=5341;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Horst U1;
RA   Basten D.E.J.W., de Groot P.W.J., Schaap P.J., Visser J.;
RT   "cDNA fragment of the gene encoding phenylalanine ammonia-lyase from
RT   Agaricus bisporus.";
RL   Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the nonoxidative deamination of L-
CC       phenylalanine to form trans-cinnamic acid and a free ammonium ion.
CC   -!- CATALYTIC ACTIVITY: L-phenylalanine = trans-cinnamate + NH(3).
CC   -!- PATHWAY: Phenylpropanoid biosynthesis; first step.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic (Probable).
CC   -!- PTM: Contains an active site 4-methylidene-imidazole-5-one (MIO),
CC       which is formed autocatalytically by cyclization and dehydration
CC       of residues Ala-Ser-Gly (By similarity).
CC   -!- SIMILARITY: Belongs to the PAL / histidase family.
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CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
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DR   EMBL; Z82018; CAB04783.1; -.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   InterPro; IPR001106; Phe/His_NH3lyase.
DR   Pfam; PF00221; PAL; 1.
DR   PROSITE; PS00488; PAL_HISTIDASE; PARTIAL.
KW   Lyase; Phenylpropanoid metabolism.
FT   NON_TER       1      1
FT   NON_TER     142    142
SQ   SEQUENCE   142 AA;  15200 MW;  93F82EAAD1E4C7F9 CRC64;
     ETGRIHHGGN FQAMAVTNAM EKTRLALHHI GKIIFAQSTE LINPATNRGL PPSLAASDPS
     LNYHVKGVDI ATAAYAAELG YLASPVSTHI QSAEMHNQAV NSMALVSARA TINSIDVLSM
     LVATYLYNLC QALDLRALQA EF
//