ID   ADH3_EMENI     STANDARD;      PRT;   352 AA.
AC   P07754;
DT   01-AUG-1988 (Rel. 08, Created)
DT   01-AUG-1988 (Rel. 08, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Alcohol dehydrogenase III (EC 1.1.1.1) (ADH III).
GN   Name=alcC; Synonyms=adh3;
OS   Emericella nidulans (Aspergillus nidulans).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; Emericella.
OX   NCBI_TaxID=162425;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=86055769; PubMed=2998782;
RA   McKnight L., Kato H., Upshall A., Parker M.D., O'Hara P.J., O'Hara S.;
RT   "Identification and molecular analysis of a third Aspergillus nidulans
RT   alcohol dehydrogenase gene.";
RL   EMBO J. 4:2093-2099(1985).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone +
CC       NADH.
CC   -!- COFACTOR: Binds 2 zinc ions per subunit.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
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DR   EMBL; X02764; CAA26541.1; -.
DR   PIR; A24648; A24648.
DR   HSSP; P39462; 1JVB.
DR   InterPro; IPR002328; ADH_zinc.
DR   InterPro; IPR002085; Adh_zn_family.
DR   InterPro; IPR011032; GroES_like.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
KW   Metal-binding; Multigene family; NAD; Oxidoreductase; Zinc.
FT   METAL        44     44       Zinc 1 (catalytic).
FT   METAL        67     67       Zinc 1 (catalytic).
FT   METAL       100    100       Zinc 2.
FT   METAL       103    103       Zinc 2.
FT   METAL       106    106       Zinc 2.
FT   METAL       114    114       Zinc 2.
FT   METAL       156    156       Zinc 1 (catalytic).
SQ   SEQUENCE   352 AA;  37126 MW;  AFDE78FE442E3144 CRC64;
     MSVPEVQWAQ VVEKAGTPPV YKQVPVPKPG PDEILVKMRY SGVCHTDLHA MKGDWPLPSK
     MPLIGGHEGA GVVVAKGELV KDEDFKIGDR AGIKWLNGSC LSCEMCMQAD EPLCPHASLS
     GYTVDGTFQQ YTIGKAALAS KIPDNVPLDA AAPILCAGIT VYKGLKESGA RPGQTVAIVG
     AGGGLGSLAQ QYAKAMGLRT IAIDSGDEKK AMCEQLGAEV FIDFSKSADV VADVKAATPG
     GLGAHAVILL AVAEKPFQQA TEYVRSHGSV VAIGLPANAF LKAPVFTTVV RMINIKGSYV
     GNRQDGVEAL DFFARGLIKA PFKKAPLQDL PQIFELMGQG KIAGRYVLEI PE
//