ID   AMDR_EMENI     STANDARD;      PRT;   765 AA.
AC   P15699;
DT   01-APR-1990 (Rel. 14, Created)
DT   01-APR-1990 (Rel. 14, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Acetamidase regulatory protein.
GN   Name=amdR; Synonyms=intA;
OS   Emericella nidulans (Aspergillus nidulans).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; Emericella.
OX   NCBI_TaxID=162425;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=90258911; PubMed=2188110;
RA   Andrianopoulos A., Hynes M.J.;
RT   "Sequence and functional analysis of the positively acting regulatory
RT   gene amdR from Aspergillus nidulans.";
RL   Mol. Cell. Biol. 10:3194-3203(1990).
CC   -!- FUNCTION: Positively regulates the expression of 5 genes involved
CC       in the catabolism of certain amides (amdS), omega amino acids
CC       (gatA and gabA), and lactams (lamA and lamB) in the presence of
CC       omega amino acid inducers.
CC   -!- SUBCELLULAR LOCATION: Nuclear.
CC   -!- SIMILARITY: Contains 1 Zn(2)-Cys(6) fungal-type binuclear cluster
CC       domain.
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DR   EMBL; M31517; AAA33294.1; -.
DR   PIR; A36332; A36332.
DR   TRANSFAC; T00931; -.
DR   InterPro; IPR007219; Fungal_trans.
DR   InterPro; IPR001138; Fungi_Trscrp_N.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   PRINTS; PR00054; FUNGALZNCYS.
DR   SMART; SM00066; GAL4; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
KW   Activator; DNA-binding; Metal-binding; Nuclear protein;
KW   Transcription regulation; Zinc.
FT   DNA_BIND     20     50       Zn(2)-Cys(6), fungal-type.
SQ   SEQUENCE   765 AA;  85837 MW;  AC50F637E8A69E08 CRC64;
     MSSTAHPTNL APSGNGSAAC VHCHRRKVRC DARLVGLPCS NCRSAGKTDC QIHEKKKKLA
     VRSILDPVPI RCRPPNPEEA PKPISSLSPS SEPPNAFTTA LRAVQSDITA PSGVANRVAH
     IRSRSSQYDT KGTRSNNNSG NNTQYQNVLP EPDSPPYSRP AASDPSEGES RADIEKRLVN
     LIDGEASDSR AIQRGVRAIY VGHELSNMSF LIRQQRDTGD DVYHFAGNEI PRRQLRTGHD
     QLLMDALTLP EPALADELVH AYFAQVNPGY PIVEEELFMS QYRNRDPADA PPILLLQTIL
     LVGAHVTRPK SERDTLKDIF FRRAKWLFDN RIERNRDILV QAALLLTWHS DLADDDVSAN
     AHYWIGIAAR IATGLGMHRN PVCTLNLEDS DVSPLTFSDF EGCGARVQAD FVIHFSELCT
     MISYIVRERF GLRISAERRK AALLEADEAL ANWSLRLPDR LRLRASDMDP WSAMLHLTYN
     NFLILLHRPH PRASAYSDDY GPHDAEICSA AAGVIASIFE ELRIHDRLKL LWYSGVHTLF
     TAMIQVRVEL RFSNPVLAIN ALRRFDSASY SLRELAQYWS HASTILRLFE ESRRLQEDLR
     TTTSDRPRRF SNLSNNSTNS PASQQKNTSG IPHLANINSS DATPPSAPSI PPLQPSSQLS
     YEVPTTESAH HNPRSQPTLS AHTHTYTTQP FDTWIPSNNL TPMDTVDNSR EMLDWRQLFS
     FTDLEGPVLP STMEGITELE DEWRQIYWQE TPMSDLLQDG GWMHG
//