ID   CHSA_EMENI     STANDARD;      PRT;  1013 AA.
AC   P30584;
DT   01-APR-1993 (Rel. 25, Created)
DT   01-OCT-1996 (Rel. 34, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Chitin synthase A (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl
DE   transferase A) (Class-II chitin synthase A).
GN   Name=chsA; Synonyms=chs2;
OS   Emericella nidulans (Aspergillus nidulans).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; Emericella.
OX   NCBI_TaxID=162425;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FGSC 89;
RX   MEDLINE=95072312; PubMed=7765508;
RA   Yanai K., Kojima N., Takaya N., Horiuchi H., Ohta A., Takagi M.;
RT   "Isolation and characterization of two chitin synthase genes from
RT   Aspergillus nidulans.";
RL   Biosci. Biotechnol. Biochem. 58:1828-1835(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE OF 303-491.
RX   MEDLINE=92115692; PubMed=1731323;
RA   Bowen A.R., Chen-Wu J.L.-P., Momany M., Young R., Szaniszlo P.J.,
RA   Robbins P.W.;
RT   "Classification of fungal chitin synthases.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:519-523(1992).
CC   -!- FUNCTION: Plays a major role in cell wall biogenesis.
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-
CC       beta-D-glucosaminyl)}(N) = UDP + {(1,4)-(N-acetyl-beta-D-
CC       glucosaminyl)}(N+1).
CC   -!- SUBCELLULAR LOCATION: Plasma membrane-bound.
CC   -!- SIMILARITY: Belongs to the chitin synthase family. Class II
CC       subfamily.
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DR   EMBL; D21268; BAA04806.1; -.
DR   EMBL; M82939; AAA33303.1; -.
DR   PIR; JC2314; JC2314.
DR   InterPro; IPR004834; Chitin_synth.
DR   InterPro; IPR001173; Glyco_trans_2.
DR   Pfam; PF01644; Chitin_synth_1; 1.
DR   ProDom; PD002998; Chitin_synth; 1.
KW   Cell wall; Glycosyltransferase; Multigene family; Transferase;
KW   Transmembrane.
FT   TRANSMEM    508    528       Potential.
FT   TRANSMEM    646    666       Potential.
FT   TRANSMEM    686    706       Potential.
FT   TRANSMEM    721    741       Potential.
FT   TRANSMEM    759    779       Potential.
FT   TRANSMEM    892    912       Potential.
FT   TRANSMEM    919    939       Potential.
SQ   SEQUENCE   1013 AA;  113679 MW;  DD5D2E9523B0778A CRC64;
     MDCQNGRRAN RTVRFARTAE SRYPERYSYE YDPEETLSRA APSMRNAPTI PPPTASGADE
     MRYTASRPAS PARPWSPTRA ADWVRPPSAA ASYYERADIN GSPRPGTPSS RYGGSPRRPL
     PPAPLFSKPG TTTQDTKIDI GDGEEDPFGG GGRTISSRHG PQGSVQSFTS ESTFIADETD
     LEKVDLDEYE EESNETKSMV DPNLHYGPAP EKQSRRGVRN AQMAKKEVQL VNGELILECK
     IPTILHSFLP RRDDREFTHM RYTAVTCDPD DFTQRGYKLR QQIGRTMRET ELFICITMYN
     EDETHFTRTM HGVMQNISHF CSRSKSRTWG KDGWKKIVVC IISDGRKKVH PRTLNALAAL
     GVYQEGIAKN VVNQKQVNAH VYEYTTQVSL DSDLKFKGAE KGIVPCQVIF CLKEHNQKKL
     NSHRWFFNAF GRALQPNICI LLDVGTRPEP TALYHLWKAF DQDSNVAGAA GEIKASKGKN
     MLGLLNPLVA SQNFEYKMSN ILDKPLESVF GYITVLPGAL SAYRFFALQN DAEGNGPLNQ
     YFKGETLHGK DADVFTANMY LAEDRILCWE LVAKREERWV LRFVKSAVGE TDVPDSIPEF
     ISQRRRWLNG AFFAAVYSIV NVKQLWKTDH SLARKILLQI ESVYQLLQLI FTYFGLANFY
     LAFFFIAGSL TDEKIDPFGH NMGKYIFIVL RYACVLVMCL QFIFSMGNRP QGAKKLYLSS
     MIVYSIVMAY TAFCTLYLIV LELMAKTGHD VPITMSDTLF VNIVVSLLST VGLYFFTSFM
     YLDPWHMFTS SAQYFALLPS YICTLQCYAF CNTHDVTWGT KGDNTINTDL GTARIINGSI
     VEVEMPSEQL DIDSGYDAAL RNLRDRLEVP DPGVSESQQQ EDYYRAVRTY MVSVWMVANV
     VLAMAVSEVY GVGSSGTNVY LAIILWSVAV LAIIRAIGST AYAVLYLIQK LVEGKAKFQA
     GNIASANASA AGSSLGTKSN VSYGSKGLNM TDRINETKWA ISRGMQKAMF WKK
//