ID   ADH1_ASPFL     STANDARD;      PRT;   349 AA.
AC   P41747;
DT   01-NOV-1995 (Rel. 32, Created)
DT   01-NOV-1995 (Rel. 32, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Alcohol dehydrogenase I (EC 1.1.1.1).
GN   Name=adh1;
OS   Aspergillus flavus.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5059;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NRRL 3357;
RX   MEDLINE=94182922; PubMed=8135521;
RA   Woloshuk C.P., Payne G.A.;
RT   "The alcohol dehydrogenase gene adh1 is induced in Aspergillus flavus
RT   grown on medium conducive to aflatoxin biosynthesis.";
RL   Appl. Environ. Microbiol. 60:670-676(1994).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone +
CC       NADH.
CC   -!- COFACTOR: Binds 2 zinc ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
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DR   EMBL; L27434; AAA32684.1; -.
DR   EMBL; L27433; AAA32683.1; -.
DR   HSSP; P39462; 1JVB.
DR   InterPro; IPR002328; ADH_zinc.
DR   InterPro; IPR002085; Adh_zn_family.
DR   InterPro; IPR011032; GroES_like.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
KW   Metal-binding; NAD; Oxidoreductase; Zinc.
FT   METAL        44     44       Zinc 1 (catalytic) (By similarity).
FT   METAL        67     67       Zinc 1 (catalytic) (By similarity).
FT   METAL        98     98       Zinc 2 (By similarity).
FT   METAL       101    101       Zinc 2 (By similarity).
FT   METAL       104    104       Zinc 2 (By similarity).
FT   METAL       112    112       Zinc 2 (By similarity).
FT   METAL       154    154       Zinc 1 (catalytic) (By similarity).
SQ   SEQUENCE   349 AA;  36901 MW;  F917FA2A03914E2F CRC64;
     MSIPEMQWAQ VAEQKGGPLI YKQIPVPKPG PDEILVKVRY SGVCHTDLHA LKGDWPLPVK
     MPLVGGHEGA GVVVARGDLV TEFEIGDHAG LKWLNGSCLA CEFCKQADEP LCPNASLSGY
     TVDGTFQQYA IGKATHASKL PKNVPLDAVA PVLCAGITVY KGLKESGVRP GQTVAIVGAG
     GGLGSLALQY AKAMGIRVVA IDGGEEKQAM CEQLGAEAYV DFTKTQDLVA DVKAATPEGL
     GAHAVILLAV AEKPFQQAAE YVSRGTVVAI GLPAGAFLRA PVFNTVVRMI NIKGSYVGNR
     QDGVEAVDFF ARGLIKAPFK TAPLQDLPKI FELMEQGKIA GRYVLEIPE
//