ID   ADH2_EMENI     STANDARD;      PRT;   367 AA.
AC   P54202;
DT   01-OCT-1996 (Rel. 34, Created)
DT   01-OCT-1996 (Rel. 34, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Alcohol dehydrogenase II (EC 1.1.1.1) (ADH II).
GN   Name=alcB;
OS   Emericella nidulans (Aspergillus nidulans).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; Emericella.
OX   NCBI_TaxID=162425;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=96418873; PubMed=8821658;
RA   Hunter G.D., Jones I.G., Sealy-Lewis H.M.;
RT   "The cloning and sequencing of the alcB gene, coding for alcohol
RT   dehydrogenase II, in Aspergillus nidulans.";
RL   Curr. Genet. 29:122-129(1996).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone +
CC       NADH.
CC   -!- COFACTOR: Binds 2 zinc ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
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DR   EMBL; Z48000; CAA88034.1; -.
DR   PIR; S62746; S62746.
DR   HSSP; P39462; 1JVB.
DR   InterPro; IPR002328; ADH_zinc.
DR   InterPro; IPR002085; Adh_zn_family.
DR   InterPro; IPR011032; GroES_like.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
KW   Metal-binding; Multigene family; NAD; Oxidoreductase; Zinc.
FT   METAL        48     48       Zinc 1 (catalytic) (By similarity).
FT   METAL        74     74       Zinc 1 (catalytic) (By similarity).
FT   METAL       107    107       Zinc 2 (By similarity).
FT   METAL       110    110       Zinc 2 (By similarity).
FT   METAL       113    113       Zinc 2 (By similarity).
FT   METAL       121    121       Zinc 2 (By similarity).
FT   METAL       163    163       Zinc 1 (catalytic) (By similarity).
SQ   SEQUENCE   367 AA;  38776 MW;  1CED337B58AF6663 CRC64;
     MAAPEIPKKQ KAVIYDNPGT VSTKVVELDV PEPGDNEVLI NLTHSGVCHS DFGIMTNTWK
     ILPFPTQPGQ VGGHEGVGKV VKLGAGAEAS GLKIGDRVGV KWISSACGQC PPCQDGADGL
     CFNQKVSGYY TPGTFQQYVL GPAQYVTPIP DGLPSAEAAP LLCAGVTVYA SLKRSKAQPG
     QWIVISGAGG GLGHLAVQIA AKGMGLRVIG VDHGSKEELV KASGAEHFVD ITKFPTGDKF
     EAISSHVKSL TTKGLGAHAV IVCTASNIAY AQSLLFLRYN GTMVCVGIPE NEPQRIASAY
     PGLFIQKHVH VTGSAVGNRN EAIETMEFAA RGVIKAHFRE EKMEALTEIF KEMEEGKLQG
     RVVLDLS
//