ID   AMDR_ASPOR     STANDARD;      PRT;   735 AA.
AC   Q06157; Q00225;
DT   01-JUN-1994 (Rel. 29, Created)
DT   01-JUN-1994 (Rel. 29, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Acetamidase regulatory protein.
GN   Name=amdR;
OS   Aspergillus oryzae.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=A1560;
RX   MEDLINE=93083975; PubMed=1452021; DOI=10.1016/0378-1119(92)90042-N;
RA   Wang X.W., Hynes M.J., Davis M.A.;
RT   "Structural and functional analysis of the amdR regulatory gene of
RT   Aspergillus oryzae.";
RL   Gene 122:147-154(1992).
CC   -!- FUNCTION: Positively regulates the expression of genes involved in
CC       the catabolism of certain amides, omega amino acids, and lactams.
CC   -!- SUBCELLULAR LOCATION: Nuclear.
CC   -!- INDUCTION: By omega amino acids.
CC   -!- SIMILARITY: Contains 1 Zn(2)-Cys(6) fungal-type binuclear cluster
CC       domain.
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DR   EMBL; M96953; AAA32686.1; ALT_SEQ.
DR   PIR; JQ1956; JQ1956.
DR   InterPro; IPR001138; Fungi_Trscrp_N.
DR   Pfam; PF00172; Zn_clus; 1.
DR   PRINTS; PR00054; FUNGALZNCYS.
DR   SMART; SM00066; GAL4; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
KW   Activator; DNA-binding; Metal-binding; Nuclear protein;
KW   Transcription regulation; Zinc.
FT   DNA_BIND     19     49       Zn(2)-Cys(6), fungal-type.
SQ   SEQUENCE   735 AA;  83196 MW;  A1473F76E965DB04 CRC64;
     MSSTAHNSQP STGNGSAACI HCHRRKVRCD ARIVGLPCSN CRSAGKADCR IHEKKKRLAV
     RSILDPVPIR CRPPPDSDST PKLLPSTPIQ PNAFTTAFRG VQPDVTSPVA AGAQIIQSPH
     SSYTNGNHLS NNRGSQPITE TQTFTRQPGA DRSMELENNA DLEKRLVKLI DEEESGSREI
     QRGVRAIYVG HELSNMSFLI RQQRDKDDDV YHFAGNEIPR RQLRTGHDQL LMDALTLPEP
     ALADELVEAY FMHVNPGYPI IEEDLFMTQY RNRDPADPPP ILLLQAILLV GAHVTRPKAE
     RDALKEIFFR RVKWLFDSRI ERNRDIMVQA ALLMTWHSDS ADDDVAANAH YWVGVAARIA
     TGLGMHRNPV STINLEDSDV SPLTPSDFEG CGSRVQAEYV IHFSELCTMI PYIVRERFGL
     RVSAERRKAA LQEADEALAN WSLKLPDSLR LRASDMDPWS AMLHLTYNNF LILLHRPHPR
     ASAYSDDYGP HDAEICSAAA GVIASIFEEL RLNDRLKFLW YSGVHTLFTA MIQVRVELRF
     SNPVLAINAL RRFDSASYSL RELAEYWSHA NTILRLFQDS KRLQEDLRMA TSERPRRFST
     HDQNKNTTNP SNPHPTPTPN LNSNTTIQSA QTEPRPPYEV PTPESPRMPP TTMSPHQNQP
     FDSWIPSSHL ASVDPIDQPR EFLDWRPVFS FTDPDQSVLP VPMEGLPELE DEWRQIYWQE
     TPMSDLLQDG GWMHG
//