ID   G3P_ASPNG      STANDARD;      PRT;   336 AA.
AC   Q12552;
DT   01-NOV-1997 (Rel. 35, Created)
DT   01-NOV-1997 (Rel. 35, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH).
GN   Name=gpdA; Synonyms=gpd;
OS   Aspergillus niger.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 9089 / N402;
RA   van Gorcom R.F.M., Punt P.J.;
RL   Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate + phosphate +
CC       NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
CC   -!- PATHWAY: Second phase of glycolysis; first step.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate
CC       dehydrogenase family.
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DR   EMBL; X99652; CAA67966.1; -.
DR   HSSP; P56649; 1DSS.
DR   InterPro; IPR000173; GAP_dhdrogenase.
DR   InterPro; IPR006424; GAPDH-I.
DR   Pfam; PF02800; Gp_dh_C; 1.
DR   Pfam; PF00044; Gp_dh_N; 1.
DR   PRINTS; PR00078; G3PDHDRGNASE.
DR   TIGRFAMs; TIGR01534; GAPDH-I; 1.
DR   PROSITE; PS00071; GAPDH; 1.
KW   Glycolysis; NAD; Oxidoreductase.
FT   BINDING     151    151       Glyceraldehyde 3-phosphate.
FT   ACT_SITE    178    178       Activates thiol group during catalysis.
SQ   SEQUENCE   336 AA;  36187 MW;  60DC0C34CCCF4840 CRC64;
     MAPKVGINGF GRIGRIVFRN AINHGEVDVV AVNDPFIETH YAAYMLKYDS THGQFKGTIE
     TYEEGLIVNG KKIRFFAERD PAAIPWGTTG ADYIVESTGV FTTQEKAAAH LKGGAKKVVI
     SAPSADAPMF VMGVNNTSYT KDINVLSNAS CTTNCLAPLA KVINDKFGIV EGLMTTVHSY
     TATQKVVDAP SSKDWRGGRT AAQNIIPSST GAAKAVGKVI PTLNGKLTGM AMRVPTSNVS
     VVDLTCRLEK ATSYDEIKKA LKDASENELK GILGYTEDDI VSSDLNGDDH SSIFDAKAGI
     ALNSNFVKLV SWYDNEWGYS RRVVDLIAYI SKVDAQ
//