ID   AMDS_ASPOR     STANDARD;      PRT;   545 AA.
AC   Q12559;
DT   28-FEB-2003 (Rel. 41, Created)
DT   28-FEB-2003 (Rel. 41, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Acetamidase (EC 3.5.1.4).
GN   Name=amdS;
OS   Aspergillus oryzae.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=RIB 40;
RX   MEDLINE=92104511; PubMed=1840550; DOI=10.1016/0378-1119(91)90491-S;
RA   Gomi K., Kitamoto K., Kumagai C.;
RT   "Cloning and molecular characterization of the acetamidase-encoding
RT   gene (amdS) from Aspergillus oryzae.";
RL   Gene 108:91-98(1991).
CC   -!- FUNCTION: Allows acetamide to be used as a sole carbon or nitrogen
CC       source.
CC   -!- CATALYTIC ACTIVITY: A monocarboxylic acid amide + H(2)O = a
CC       monocarboxylate + NH(3).
CC   -!- SIMILARITY: Belongs to the amidase family.
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DR   EMBL; D10492; BAA01373.1; -.
DR   PIR; JS0633; JS0633.
DR   InterPro; IPR000120; Amidase.
DR   Pfam; PF01425; Amidase; 1.
DR   PROSITE; PS00571; AMIDASES; 1.
KW   Hydrolase.
FT   ACT_SITE    130    130       Charge relay system (By similarity).
FT   ACT_SITE    205    205       Charge relay system (By similarity).
FT   ACT_SITE    229    229       Acyl-ester intermediate (By similarity).
SQ   SEQUENCE   545 AA;  60156 MW;  1DDFFCBCC7492C5B CRC64;
     MPSASWEDLA ADKRARLEKS IPDEWKFKSV PIEGSVIDLP EKSGILSPSE IKITNSSATE
     LVAQLANGTL KSVDVTLAFC KRAALAHQLV NCAHDFFPEL ALAQARELDR YFETHKKPVG
     PLHGLPISLK DQLRVKGTET CMAYISWLGK RDTSDSILTA LLRKAGAVFL VKTSVPQTLM
     VCETVNNIIG RTSNPRNLNL SCGGSSGGEG AMIAMRGGAI GIGTDIGGSI RVPAAFNSLY
     GIRPSHDRLP YGGMTNSMEG QETIHSVVGP IAHSAQDVRL FLQSVLKEEP WKYDSKVIPL
     PWREAEENAA QAKIAEKSLN FAFYDFDGVV RPHPPITRGV EIVRSTLEKD GHTVAPWTPY
     KHAFAVDLAN KIYAADGSTD VYKHINASGE PAIPNIKDLM NPNLPKADLN EVWDAQLQKW
     RYQCEYLDKW REWEERTGKE LDAIIAPVAA TAAVRHNQFR YYGYATVFNV LDYTSVVVPV
     TYADKAVDHR LADYQPVSDM DKAVYAEYDP EVYHGAPVAV QIIGRRLSEE RTLAIAEYVG
     KLLGH
//