ID   CHSC_ASPFU     STANDARD;      PRT;   889 AA.
AC   Q92197;
DT   15-JUL-1999 (Rel. 38, Created)
DT   15-JUL-1999 (Rel. 38, Last sequence update)
DT   25-JAN-2005 (Rel. 46, Last annotation update)
DE   Chitin synthase C (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl
DE   transferase C) (Class-III chitin synthase C).
GN   Name=chsC;
OS   Aspergillus fumigatus (Sartorya fumigata).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=5085;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=H237;
RX   MEDLINE=96347138; PubMed=8736545;
RA   Mellado E., Aufauvre-Brown A., Gow N.A.R., Holden D.W.;
RT   "The Aspergillus fumigatus chsC and chsG genes encode class III chitin
RT   synthases with different functions.";
RL   Mol. Microbiol. 20:667-679(1996).
CC   -!- FUNCTION: Plays a major role in cell wall biogenesis.
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-
CC       beta-D-glucosaminyl)}(N) = UDP + {(1,4)-(N-acetyl-beta-D-
CC       glucosaminyl)}(N+1).
CC   -!- SUBCELLULAR LOCATION: Plasma membrane-bound.
CC   -!- SIMILARITY: Belongs to the chitin synthase family. Class III
CC       subfamily.
CC   --------------------------------------------------------------------------
CC   This SWISS-PROT entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use  by  non-profit  institutions as long  as its content  is  in  no  way
CC   modified and this statement is not removed.  Usage  by  and for commercial
CC   entities requires a license agreement (See http://www.isb-sib.ch/announce/
CC   or send an email to license@isb-sib.ch).
CC   --------------------------------------------------------------------------
DR   EMBL; X94245; CAA63929.1; -.
DR   PIR; JC6015; JC6015.
DR   InterPro; IPR004834; Chitin_synth.
DR   Pfam; PF01644; Chitin_synth_1; 1.
DR   ProDom; PD002998; Chitin_synth; 1.
KW   Cell wall; Glycosyltransferase; Multigene family; Transferase;
KW   Transmembrane.
FT   TRANSMEM    565    585       Potential.
FT   TRANSMEM    606    626       Potential.
FT   TRANSMEM    636    656       Potential.
FT   TRANSMEM    686    706       Potential.
FT   TRANSMEM    717    737       Potential.
FT   TRANSMEM    818    838       Potential.
FT   TRANSMEM    857    877       Potential.
SQ   SEQUENCE   889 AA;  100756 MW;  0735AEFD82917FEA CRC64;
     MGTPRPYSAH SPQESRSSFY SQPSQSPTQP TYGRDDAEDQ QQSLLRRSLA SPNGWSYDDP
     NVSTDSLRRY TLHDPGITAF APPYPESEAA DVRSARMSGY SGIEMDAWQR RQGVKPSALR
     RYGTRKINLV QGSVLSVDYP VPSAIQNAIQ AEYRDAEEAF HEEFTHMRYT AATCDPDEFT
     LRNGYNLRPA MYNRHTERLI AITYYNEDKV LTARTLHGVM QNVRDIVNLK KSEFWNKGGP
     AWQKIVVCLV FDGIEPCDKN TLDVLATIGV YQDGVMKKDV DGRETVAHIF EYTTQLSVTP
     TQQLVRPQPN DPSNLPPVQM LFCLKQKNSK KINSHRWLFN AFSRILNPEI CILLDAGTKP
     GSKSLLALWE AFYNDKTLGG ACGEIHAMLG RGWRNVLNPL VAAQNFEYKI SNILDKPLES
     AFGYVSVLPG AFSAYRYRAI MGRPLEQYFH GDHTLSKRLG KKGIEGMNIF KKNMFLAEDR
     ILCFELVAKA GYKWHLTYVK ASKGETDVPE AAPEYISQRR RWLNGSFAAS LYSIMHFGRI
     YKSGHSFVRM FFLHIQMIYN CCQLIMTWFS LASYWLTSSV IMDLVGTPSS HNKYKAWPFG
     NDASPIVNFF VKYGYLLVLM LQFVLALGNR PKAYTMSFLW FSLVQFYVLI LSFYLVANAF
     MGGMIDFDFD QGVGNFLSSF FSSTGGGIVL IALVSTYGIY IVASILYMDP WHILTSSWAY
     FLGMTTSINI LMVYAFCNWH DVSWGTKGSD KADALPSAQT KKADASKSNF IEEIDKPQAD
     IDSQFEATVK RRLAPYQEPK EDSTISLDDS YRNFRTSLVL LWILSNLLVS LLITSDGIRK
     MCLTNTSTTR TQYYFQVILW ATAGLSIFRF IGSIYFLGKS GILCCVTRR
//