ID   CYC4_AZOVI     STANDARD;      PRT;   210 AA.
AC   P43302;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   16-MAY-2006, entry version 45.
DE   Cytochrome c4 precursor.
GN   Name=cycA;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CA;
RX   MEDLINE=95345104; PubMed=7619830; DOI=10.1016/0005-2728(95)00043-I;
RA   Ng T.C.N., Laheri A.N., Maier R.J.;
RT   "Cloning, sequencing, and mutagenesis of the cytochrome c4 gene from
RT   Azotobacter vinelandii: characterization of the mutant strain and a
RT   proposed new branch in the respiratory chain.";
RL   Biochim. Biophys. Acta 1230:119-129(1995).
RN   [2]
RP   PROTEIN SEQUENCE OF 21-210.
RC   STRAIN=ATCC 13705 / OP1 / DSM 366 / NCIB 11614 / LMG 3878 / UW;
RX   MEDLINE=84307416; PubMed=6089759;
RA   Ambler R.P., Daniel M., Melis K., Stout C.D.;
RT   "The amino acid sequence of the dihaem cytochrome c4 from the
RT   bacterium Azotobacter vinelandii.";
RL   Biochem. J. 222:217-227(1984).
CC   -!- FUNCTION: Diheme, high potential cytochrome c believed to be an
CC       intermediate electron donor to terminal oxidation systems.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- PTM: Binds 2 heme groups per subunit.
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DR   EMBL; L37290; AAA87314.1; -; Genomic_DNA.
DR   PIR; I39740; I39740.
DR   HSSP; Q52369; 1ETP.
DR   SMR; P43302; 21-210.
DR   InterPro; IPR008169; Cyt_C_bact.
DR   InterPro; IPR009056; Cyt_c_monohaem.
DR   InterPro; IPR003088; Cyt_CI.
DR   InterPro; IPR008168; Cyt_CIC.
DR   InterPro; IPR012126; Cytochrome_c4.
DR   InterPro; IPR012282; Cytochrome_c_R.
DR   Pfam; PF00034; Cytochrom_C; 1.
DR   PIRSF; PIRSF000005; Cytochrome_c4; 1.
DR   PRINTS; PR00605; CYTCHROMECIC.
DR   ProDom; PD004020; Cyt_C_bact; 2.
DR   PROSITE; PS51007; CYTC; 2.
KW   Direct protein sequencing; Electron transport; Heme; Iron;
KW   Metal-binding; Periplasmic; Signal; Transport.
FT   SIGNAL        1     20
FT   CHAIN        21    210       Cytochrome c4.
FT                                /FTId=PRO_0000006507.
FT   METAL        38     38       Iron (heme 1 axial ligand).
FT   METAL        86     86       Iron (heme 1 axial ligand).
FT   METAL       143    143       Iron (heme 2 axial ligand).
FT   METAL       187    187       Iron (heme 2 axial ligand).
FT   BINDING      34     34       Heme 1 (covalent).
FT   BINDING      37     37       Heme 1 (covalent).
FT   BINDING     139    139       Heme 2 (covalent).
FT   BINDING     142    142       Heme 2 (covalent).
SQ   SEQUENCE   210 AA;  21687 MW;  4B09C4AA90D1FC74 CRC64;
     MNKALVTLLL TLGITGLAHA AGDAAAGQGK AAVCGACHGP DGNSAAPNFP KLAGQGERYL
     LKQMQDIKAG TKPGAPEGSG RKVLEMTGML DNFSDQDLAD LAAYFTSQKP TVGAADPQLV
     EAGETLYRGG KLADGMPACT GCHSPNGEGN TPAAYPRLSG QHAQYVAKQL TDFREGARTN
     DGDNMIMRSI AAKLSNKDIA AISSYIQGLH
//