ID   ALG8_AZOVI     STANDARD;      PRT;   492 AA.
AC   P94199;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   21-MAR-2006, entry version 26.
DE   Glycosyl transferase alg8 (EC 2.4.1.-).
GN   Name=alg8;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 9046;
RX   MEDLINE=98019097; PubMed=9358065; DOI=10.1016/S0378-1119(97)00380-6;
RA   Mejia-Ruiz H., Guzman J., Moreno S., Soberon-Chavez G., Espin G.;
RT   "The Azotobacter vinelandii alg8 and alg44 genes are essential for
RT   alginate synthesis and can be transcribed from an algD-independent
RT   promoter.";
RL   Gene 199:271-277(1997).
CC   -!- FUNCTION: Possibly a processive enzyme that polymerizes GDP-
CC       mannuronic acid.
CC   -!- PATHWAY: Alginate biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Bacterial cell membrane; multi-pass membrane
CC       protein (Potential).
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
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DR   EMBL; Y08819; CAA70053.1; -; Genomic_DNA.
KW   Alginate biosynthesis; Glycosyltransferase; Membrane; Transferase;
KW   Transmembrane.
FT   CHAIN         1    492       Glycosyl transferase alg8.
FT                                /FTId=PRO_0000059253.
FT   TRANSMEM     13     32       Potential.
FT   TRANSMEM     47     69       Potential.
FT   TRANSMEM    379    401       Potential.
FT   TRANSMEM    421    443       Potential.
SQ   SEQUENCE   492 AA;  56284 MW;  9E54A4733CD1BE14 CRC64;
     MDRLKHALGE ATGWLLFLSF LMLVAVALPP QVFDPESKHF IMLIGLIGVW RYSMGIIHFL
     RGMLFLYVVY PYYRRKVEKL GKDADPSHVF LMVTSFRIDA LTTGKVYGSV IKEAINCGYP
     TTVVCSIVEM SDELLIKSLW EKLDPPDRVK LDFVRIAGTG KRDGLANGFR AISRHMPDED
     AVVAVIDGDT VLNEGVVRKT VPLFQDLPQH GWPDHQRILR SAGRLRHERV AQVRFAQRHI
     NMCSMALSHR VLTLTGRMSV FRAVVTDPEF IVDVENDNLD HWRLGRFKFL TGDDKSSWFS
     LMRLGYDTFY VPDASIHTVE HPPEKRFVKA SRKLMFRWYG NNLRQNSRAL KLGVQRLGWF
     TSVVLFDQRV SMWTSLLGLT VAIIGSIKYS IAIFIAYLLW VCSTRLVLTL LLSLSGHPIG
     PAYPLILYYN QIVGAVVKIH VFFRLDQQSW TRQDTKLNRE LASFQSWFNN WSSKAMTFSA
     TSIFIAVLML SV
//