ID   CYDA_AZOVI     STANDARD;      PRT;   537 AA.
AC   Q09049;
DT   01-NOV-1997 (Rel. 35, Created)
DT   01-NOV-1997 (Rel. 35, Last sequence update)
DT   05-JUL-2004 (Rel. 44, Last annotation update)
DE   Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-).
GN   Name=cydA;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CA;
RX   MEDLINE=92011387; PubMed=1655703;
RA   Moshiri F., Chawla A., Maier R.J.;
RT   "Cloning, characterization, and expression in Escherichia coli of the
RT   genes encoding the cytochrome d oxidase complex from Azotobacter
RT   vinelandii.";
RL   J. Bacteriol. 173:6230-6241(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CA;
RX   MEDLINE=92078187; PubMed=1660468;
RA   Moshiri F., Smith E.G., Taormino J.P., Maier R.J.;
RT   "Transcriptional regulation of cytochrome d in nitrogen-fixing
RT   Azotobacter vinelandii. Evidence that up-regulation during N2 fixation
RT   is independent of nifA but dependent on ntrA.";
RL   J. Biol. Chem. 266:23169-23174(1991).
RN   [3]
RP   CHARACTERIZATION.
RX   MEDLINE=91008979; PubMed=2170336;
RA   Kelly M.J.S., Poole R.K., Yates M.G., Kennedy C.;
RT   "Cloning and mutagenesis of genes encoding the cytochrome bd terminal
RT   oxidase complex in Azotobacter vinelandii: mutants deficient in the
RT   cytochrome d complex are unable to fix nitrogen in air.";
RL   J. Bacteriol. 172:6010-6019(1990).
CC   -!- FUNCTION: May be involved in maintaining the low intracellular
CC       oxygen concentration required for nitrogen fixation.
CC   -!- CATALYTIC ACTIVITY: Ubiquinol-8 + O(2) = Ubiquinone-8 + H(2)O.
CC   -!- COFACTOR: Contains the protoheme IX center b558.
CC   -!- SUBUNIT: Heterodimer of subunits I and II.
CC   -!- SUBCELLULAR LOCATION: Integral membrane protein. Inner membrane.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; M77787; AAA22123.1; -.
DR   EMBL; S57066; AAB19986.1; -.
DR   PIR; A38170; A38170.
DR   InterPro; IPR002585; Bac_Ubq_Cox.
DR   Pfam; PF01654; Bac_Ubq_Cox; 1.
KW   Electron transport; Heme; Inner membrane; Oxidoreductase;
KW   Transmembrane.
FT   DOMAIN        1     24       Cytoplasmic (Potential).
FT   TRANSMEM     25     44       Potential.
FT   DOMAIN       45     96       Periplasmic (Potential).
FT   TRANSMEM     97    116       Potential.
FT   DOMAIN      117    131       Cytoplasmic (Potential).
FT   TRANSMEM    132    151       Potential.
FT   DOMAIN      152    189       Periplasmic (Potential).
FT   TRANSMEM    190    209       Potential.
FT   DOMAIN      210    221       Cytoplasmic (Potential).
FT   TRANSMEM    222    241       Potential.
FT   DOMAIN      242    394       Periplasmic (Potential).
FT   TRANSMEM    395    414       Potential.
FT   DOMAIN      415    472       Cytoplasmic (Potential).
FT   TRANSMEM    473    492       Potential.
FT   DOMAIN      493    537       Periplasmic (Potential).
FT   METAL       188    188       Iron (heme b558 axial ligand) (By
FT                                similarity).
SQ   SEQUENCE   537 AA;  59719 MW;  8F78A49F6AB4902E CRC64;
     MISESVVDLS RLQFAMTALY HFLFVPLTLG MTFLLAIMES VYVMTGKQVY KDMVKFWGKL
     FGINFALGVT TGITMEFQFG TNWAYYSHYV GDIFGAPLAI EGLTAFFLES TFIGMFFFGW
     DRLSKIQHLA VTWLVALGSN LSALWILVAN GWMQHPVGAE FNFETMRMEL VDFGALLLNP
     VAQVKFVHTV ASGYVTGAVF VLAISSYYLL KKRDLGFARR SFAIASAFGM ASILSVIVLG
     DESGYEVGEV QKAKLAAIEA EWETHPAPAS FTLIGFPNEE EQRTDFAVKI PWVLGIIATR
     SLDEQVIGIK DLIADHEARI RNGMVRYGLL EELRAGNKSP EKIAAFNEVK DDLGYGLLLK
     KYTPNVVDAS EEQIKQAAKD TIPSVASMFW SFRAMVGAGF AMLILFVCAF WASARKNEES
     KPWLLKFALY SLPLPWIATQ TGWFVAEHGR QPWTIGGVLP THLSASSLST GDLWGSLIAL
     IAFYTLLLVV EMYLMIRFAR LGPSSLHTGR YHFEQLEQHA VKHASPSQAD PQQPVNA
//