ID   CYDA_AZOVI     STANDARD;      PRT;   537 AA.
AC   Q09049;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   07-MAR-2006, entry version 32.
DE   Cytochrome d ubiquinol oxidase subunit 1 (EC 1.10.3.-) (Cytochrome d
DE   ubiquinol oxidase subunit I).
GN   Name=cydA;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CA;
RX   MEDLINE=92011387; PubMed=1655703;
RA   Moshiri F., Chawla A., Maier R.J.;
RT   "Cloning, characterization, and expression in Escherichia coli of the
RT   genes encoding the cytochrome d oxidase complex from Azotobacter
RT   vinelandii.";
RL   J. Bacteriol. 173:6230-6241(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CA;
RX   MEDLINE=92078187; PubMed=1660468;
RA   Moshiri F., Smith E.G., Taormino J.P., Maier R.J.;
RT   "Transcriptional regulation of cytochrome d in nitrogen-fixing
RT   Azotobacter vinelandii. Evidence that up-regulation during N2 fixation
RT   is independent of nifA but dependent on ntrA.";
RL   J. Biol. Chem. 266:23169-23174(1991).
RN   [3]
RP   CHARACTERIZATION.
RX   MEDLINE=91008979; PubMed=2170336;
RA   Kelly M.J.S., Poole R.K., Yates M.G., Kennedy C.;
RT   "Cloning and mutagenesis of genes encoding the cytochrome bd terminal
RT   oxidase complex in Azotobacter vinelandii: mutants deficient in the
RT   cytochrome d complex are unable to fix nitrogen in air.";
RL   J. Bacteriol. 172:6010-6019(1990).
CC   -!- FUNCTION: May be involved in maintaining the low intracellular
CC       oxygen concentration required for nitrogen fixation.
CC   -!- CATALYTIC ACTIVITY: Ubiquinol-8 + O(2) = Ubiquinone-8 + H(2)O.
CC   -!- COFACTOR: Binds 1 protoheme IX.
CC   -!- SUBUNIT: Heterodimer of subunits I and II.
CC   -!- SUBCELLULAR LOCATION: Bacterial cell inner membrane; multi-pass
CC       membrane protein.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; M77787; AAA22123.1; -; Genomic_DNA.
DR   EMBL; S57066; AAB19986.1; -; Genomic_DNA.
DR   PIR; A38170; A38170.
DR   InterPro; IPR002585; Bac_Ubq_Cox.
DR   Pfam; PF01654; Bac_Ubq_Cox; 1.
KW   Electron transport; Heme; Inner membrane; Iron; Membrane;
KW   Metal-binding; Oxidoreductase; Transmembrane; Transport.
FT   CHAIN         1    537       Cytochrome d ubiquinol oxidase subunit 1.
FT                                /FTId=PRO_0000183917.
FT   TOPO_DOM      1     24       Cytoplasmic (Potential).
FT   TRANSMEM     25     44       Potential.
FT   TOPO_DOM     45     96       Periplasmic (Potential).
FT   TRANSMEM     97    116       Potential.
FT   TOPO_DOM    117    131       Cytoplasmic (Potential).
FT   TRANSMEM    132    151       Potential.
FT   TOPO_DOM    152    189       Periplasmic (Potential).
FT   TRANSMEM    190    209       Potential.
FT   TOPO_DOM    210    221       Cytoplasmic (Potential).
FT   TRANSMEM    222    241       Potential.
FT   TOPO_DOM    242    394       Periplasmic (Potential).
FT   TRANSMEM    395    414       Potential.
FT   TOPO_DOM    415    472       Cytoplasmic (Potential).
FT   TRANSMEM    473    492       Potential.
FT   TOPO_DOM    493    537       Periplasmic (Potential).
FT   METAL       188    188       Iron (heme b558 axial ligand) (By
FT                                similarity).
SQ   SEQUENCE   537 AA;  59719 MW;  8F78A49F6AB4902E CRC64;
     MISESVVDLS RLQFAMTALY HFLFVPLTLG MTFLLAIMES VYVMTGKQVY KDMVKFWGKL
     FGINFALGVT TGITMEFQFG TNWAYYSHYV GDIFGAPLAI EGLTAFFLES TFIGMFFFGW
     DRLSKIQHLA VTWLVALGSN LSALWILVAN GWMQHPVGAE FNFETMRMEL VDFGALLLNP
     VAQVKFVHTV ASGYVTGAVF VLAISSYYLL KKRDLGFARR SFAIASAFGM ASILSVIVLG
     DESGYEVGEV QKAKLAAIEA EWETHPAPAS FTLIGFPNEE EQRTDFAVKI PWVLGIIATR
     SLDEQVIGIK DLIADHEARI RNGMVRYGLL EELRAGNKSP EKIAAFNEVK DDLGYGLLLK
     KYTPNVVDAS EEQIKQAAKD TIPSVASMFW SFRAMVGAGF AMLILFVCAF WASARKNEES
     KPWLLKFALY SLPLPWIATQ TGWFVAEHGR QPWTIGGVLP THLSASSLST GDLWGSLIAL
     IAFYTLLLVV EMYLMIRFAR LGPSSLHTGR YHFEQLEQHA VKHASPSQAD PQQPVNA
//