ID   ADHB_BACSU     STANDARD;      PRT;   390 AA.
AC   O05240;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   07-MAR-2006, entry version 36.
DE   Probable NADH-dependent butanol dehydrogenase 2 (EC 1.1.1.-).
GN   Name=yugK; OrderedLocusNames=BSU31360;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   MEDLINE=97419515; PubMed=9274030;
RA   Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M.,
RA   Hilbert H., Duesterhoeft A., Pohl T.M., Weitzenegger T.;
RT   "Analysis of the Bacillus subtilis genome: cloning and nucleotide
RT   sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees
RT   (pai).";
RL   Microbiology 143:2769-2774(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA   Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA   Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA   Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA   Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA   Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T.,
RA   Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA   Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA   Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA   Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA   Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M.,
RA   Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M.,
RA   Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S.,
RA   Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G.,
RA   Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B.,
RA   Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R.,
RA   Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P.,
RA   Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H.,
RA   Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P.,
RA   Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F.,
RA   Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H.,
RA   Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- PATHWAY: Butanol formation; final step.
CC   -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC       family.
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DR   EMBL; Z93934; CAB07923.1; -; Genomic_DNA.
DR   EMBL; Z99120; CAB15125.1; -; Genomic_DNA.
DR   PIR; B70011; B70011.
DR   SubtiList; BG12365; yugK.
DR   GenomeReviews; AL009126_GR; BSU31360.
DR   BioCyc; BSUB1423:BSU3131-MONOMER; -.
DR   InterPro; IPR001670; Fe_ADH.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
DR   PROSITE; PS00060; ADH_IRON_2; 1.
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    390       Probable NADH-dependent butanol
FT                                dehydrogenase 2.
FT                                /FTId=PRO_0000087820.
SQ   SEQUENCE   390 AA;  43406 MW;  027D3CD5CD8BA52F CRC64;
     MENFTYYNPT KLIFGKGQLE QLRKEFKRYG KNVLLVYGGG SIKRNGLYDQ VTGILKEEGA
     VVHELSGVEP NPRLATVEKG IGLCREHDID FLLAVGGGSV IDCTKAIAAG VKYDGDAWDI
     FSKKVTAEDA LPFGTVLTLA ATGSEMNPDS VITNWETNEK FVWGSNVTHP RFSILDPENT
     FTVPENQTVY GMVDMMSHVF EQYFHNVENT PLQDRMCFAV LQTVIETAPK LLEDLENYEL
     RETILYAGTI ALNGTLQMGY FGDWASHTME HAVSAVYDIP HAGGLAILFP NWMRYTLDTN
     VGRFKNLMLN MFDIDTEGKT DKEIALEGID KLSAFWTSLG APSRLADYNI GEEKLELIAD
     IAAKEMEHGG FGNFQKLNKD DVLAILRASL
//