ID   BOFA_BACSU     STANDARD;      PRT;    87 AA.
AC   P24282;
DT   01-MAR-1992 (Rel. 21, Created)
DT   01-MAR-1992 (Rel. 21, Last sequence update)
DT   01-FEB-2005 (Rel. 46, Last annotation update)
DE   Sigma-K factor processing regulatory protein BOFA (Bypass-of-forespore
DE   protein A).
GN   Name=bofA; OrderedLocusNames=BSU00230;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=91088245; PubMed=2124672;
RA   Alonso C., Shirahige K., Ogasawara N.;
RT   "Molecular cloning, genetic characterization and DNA sequence analysis
RT   of the recM region of Bacillus subtilis.";
RL   Nucleic Acids Res. 18:6771-6777(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=168;
RX   MEDLINE=96051385; PubMed=7584024;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus
RT   subtilis chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA   Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA   Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA   Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA   Choi S.K., Codani J.J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA   Denizot F., Devine K.M., Dusterhoft A., Ehrlich S.D., Emmerson P.T.,
RA   Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA   Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA   Ghim S.Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA   Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA   Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M.,
RA   Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M.,
RA   Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S.,
RA   Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G.,
RA   Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B.,
RA   Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R.,
RA   Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P.,
RA   Shin B.S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H.,
RA   Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P.,
RA   Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F.,
RA   Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H.,
RA   Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   CHARACTERIZATION.
RX   MEDLINE=92250411; PubMed=1577688;
RA   Ricca E., Cutting S.M., Losick R.;
RT   "Characterization of bofA, a gene involved in intercompartmental
RT   regulation of pro-sigma K processing during sporulation in Bacillus
RT   subtilis.";
RL   J. Bacteriol. 174:3177-3184(1992).
RN   [5]
RP   TOPOLOGY.
RX   MEDLINE=97286525; PubMed=9141672;
RA   Varcamonti M., Marasco R., de Felice M., Sacco M.;
RT   "Membrane topology analysis of the Bacillus subtilis BofA protein
RT   involved in pro-sigma K processing.";
RL   Microbiology 143:1053-1058(1997).
CC   -!- FUNCTION: Involved in the mediation of the intercompartmental
CC       coupling of pro-sigma K processing to events in the forespore.
CC   -!- SUBCELLULAR LOCATION: Integral membrane protein.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; X17014; CAA34880.1; -.
DR   EMBL; D26185; BAA05259.1; -.
DR   EMBL; Z99104; CAB11799.1; -.
DR   PIR; B41869; B41869.
DR   SubtiList; BG10087; bofA.
DR   InterPro; IPR010001; BofA.
DR   Pfam; PF07441; BofA; 1.
KW   Complete proteome; Sporulation; Transmembrane.
FT   DOMAIN        1      2       Extracellular (Probable).
FT   TRANSMEM      3     23       Probable.
FT   DOMAIN       24     36       Cytoplasmic (Probable).
FT   TRANSMEM     37     57       Probable.
FT   DOMAIN       58     87       Extracellular (Probable).
SQ   SEQUENCE   87 AA;  9010 MW;  FF1DA14E6826B70E CRC64;
     MEPIFIIGII LGLVILLFLS GSAAKPLKWI GITAVKFVAG ALLLVCVNMF GGSLCIHVPI
     NLVTTAISGI LGIPGIAALV VIKQFII
//