ID   ADEC_BACHD     STANDARD;      PRT;   585 AA.
AC   Q9KF46;
DT   25-OCT-2004 (Rel. 45, Created)
DT   25-OCT-2004 (Rel. 45, Last sequence update)
DT   25-OCT-2004 (Rel. 45, Last annotation update)
DE   Adenine deaminase (EC 3.5.4.2) (Adenase) (Adenine aminase).
GN   Name=ade; Synonyms=adeC; OrderedLocusNames=BH0640;
OS   Bacillus halodurans.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=86665;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-125 / JCM 9153;
RX   MEDLINE=20512582; PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N.,
RA   Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S.,
RA   Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus
RT   halodurans and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- CATALYTIC ACTIVITY: Adenine + H(2)O = hypoxanthine + NH(3).
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- SIMILARITY: Belongs to the adenine deaminase family.
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DR   EMBL; AP001509; BAB04359.1; -.
DR   PIR; H83729; H83729.
DR   HAMAP; MF_01518; -; 1.
DR   InterPro; IPR006679; Adenine_deam.
DR   InterPro; IPR006680; Amidohydro_1.
DR   InterPro; IPR005847; DHOase.
DR   InterPro; IPR011059; Metalo_hydrolase.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   ProDom; PD001248; Amidohydro_like; 1.
DR   TIGRFAMs; TIGR01178; ade; 1.
KW   Complete proteome; Hydrolase; Manganese.
SQ   SEQUENCE   585 AA;  63055 MW;  A6041ED63699655D CRC64;
     MTDRLERKLA IAANQDKADL LIKNGQIVDV FQLETFEGDV VIADGEIVAI SDPGTYEAHE
     EVDAKGAFIA PAFIDGHVHI ESSMVAPEQF AKVVVPHGVT TVIADPHEIA NVAGVQGVEY
     MLDASEGIPL DVKMMVPSCV PATPFEHSGA RLTAEEVAEL FRDPRIFGLG EVMDYPAVLT
     RDQEMMAKLK AAHSEGRIVD GHGAGLDSVA LNAYTAAGIG NDHEAVTPEE AKARLQRGMY
     LLIREGTAAK DFDALMKAIT PMNSRRALFV TDDKHLDELV EEGSIDHHVR KAIQIGVNPL
     QAIQMASLNA AECFKLAKKG AIAPGFTADL LFIEDLQSLA ITHVFKNGTC VAKNGKLIVP
     IRETVQPPQR LLESVNMKLV TKEQLELSLQ SDEEAHLIQI QPGSIVTKHI REKVAVKDGV
     FIPSVARDQL KLVVAERHHK RGTVGVGIVK GFGLTKGAIA TTVAHDSHNI VAVGTNDEDL
     LAAIKELENI QGGMTIVKDG KVLVSLPLTI GGLMSDQSYD VVCEQIKSVD AAIGALGFVG
     DFNPFLTLSF LALPVIPEIK LTDQGLFDVT SFSFIDQQVY AEETN
//