ID   ALR_BACHD      STANDARD;      PRT;   388 AA.
AC   Q9KFF9;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   21-MAR-2006, entry version 34.
DE   Alanine racemase (EC 5.1.1.1).
GN   Name=alr; OrderedLocusNames=BH0520;
OS   Bacillus halodurans.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=86665;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-125 / JCM 9153;
RX   MEDLINE=20512582; PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N.,
RA   Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S.,
RA   Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus
RT   halodurans and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Provides the D-alanine required for cell wall
CC       biosynthesis (By similarity).
CC   -!- CATALYTIC ACTIVITY: L-alanine = D-alanine.
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- PATHWAY: D-alanine branch of peptidoglycan biosynthesis; first
CC       step.
CC   -!- SIMILARITY: Belongs to the alanine racemase family.
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DR   EMBL; BA000004; BAB04239.1; -; Genomic_DNA.
DR   PIR; H83714; H83714.
DR   HSSP; P10724; 1BD0.
DR   GenomeReviews; BA000004_GR; BH0520.
DR   BioCyc; BHAL86665:BH0520-MONOMER; -.
DR   HAMAP; MF_01201; -; 1.
DR   InterPro; IPR012155; Ala_racemase.
DR   InterPro; IPR011079; Ala_racemase_C.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR000821; Ala_racemase_reg.
DR   InterPro; IPR009006; Racem_decarbox_C.
DR   Pfam; PF00842; Ala_racemase_C; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PIRSF; PIRSF001401; Ala_racemase; 1.
DR   PRINTS; PR00992; ALARACEMASE.
DR   TIGRFAMs; TIGR00492; alr; 1.
DR   PROSITE; PS00395; ALANINE_RACEMASE; 1.
KW   Cell shape; Cell wall; Complete proteome; Isomerase;
KW   Peptidoglycan synthesis; Pyridoxal phosphate.
FT   CHAIN         1    388       Alanine racemase.
FT                                /FTId=PRO_0000114497.
FT   ACT_SITE     40     40       Proton acceptor; specific for D-alanine
FT                                (By similarity).
FT   ACT_SITE    269    269       Proton acceptor; specific for L-alanine
FT                                (By similarity).
FT   BINDING      40     40       Pyridoxal phosphate (covalent) (By
FT                                similarity).
SQ   SEQUENCE   388 AA;  44021 MW;  8017C15D03C9A66A CRC64;
     MEHFYRDTWV EVDLDAIEQN VTNALRLYKD REMNLMAVVK ANGYGHGAVE VSQAALRAGA
     SYLSVAFLDE ALALRKAGID APILVMGLVG AEHVQLAIKH RITLTVYQLD WLEQAISRLH
     TRDKLAIHLK LDTGMGRIGL RRKEDIRSCM DFIASHECFE LEGVFTHFAT ADEKDLTYFK
     KQCQRFNQWL EYIREWQLPI RYVHCGNSAA GLRFPEKNFN MFRFGIAMYG LTPSPEITDE
     LPFPLKQAFS LKSRLSNVKK LPKGEGISYG ATYVTEGAEW IGTLPIGYAD GWIRHHSNAG
     GHVLIDGKRA PFVGRICMDQ CMIRLPKKHS IGDTVTLIGE SDGKQITMDE VAKRLNTINY
     EIPCVISWRV PRIYFRDGQI ISVKNNLL
//