ID CH60_BURTH STANDARD; PRT; 546 AA. AC P58723; DT 31-JAN-2002, integrated into UniProtKB/Swiss-Prot. DT 31-JAN-2002, sequence version 1. DT 18-APR-2006, entry version 29. DE 60 kDa chaperonin (Protein Cpn60) (groEL protein). GN Name=groL; Synonyms=groEL; OS Burkholderia thailandensis. OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Burkholderia; pseudomallei group. OX NCBI_TaxID=57975; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=12458120; DOI=10.1016/S0732-8893(02)00439-X; RA Woo P.C.Y., Woo G.K.S., Lau S.K.P., Wong S.S.Y., Yuen K.-Y.; RT "Single gene target bacterial identification. GroEL gene sequencing RT for discriminating clinical isolates of Burkholderia pseudomallei and RT Burkholderia thailandensis."; RL Diagn. Microbiol. Infect. Dis. 44:143-149(2002). CC -!- FUNCTION: Prevents misfolding and promotes the refolding and CC proper assembly of unfolded polypeptides generated under stress CC conditions (By similarity). CC -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of CC 7 subunits (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the chaperonin (HSP60) family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF454383; AAL49762.1; -; Genomic_DNA. DR HSSP; P06139; 1GR5. DR SMR; P58723; 2-526. DR HAMAP; MF_00600; -; 1. DR InterPro; IPR001844; Chaprnin_Cpn60. DR InterPro; IPR002423; Cpn60/TCP-1. DR InterPro; IPR012723; GroEL. DR InterPro; IPR008950; GroEL-ATPase. DR PANTHER; PTHR11353; Cpn60/TCP-1; 1. DR Pfam; PF00118; Cpn60_TCP1; 1. DR PRINTS; PR00298; CHAPERONIN60. DR PRINTS; PR00304; TCOMPLEXTCP1. DR TIGRFAMs; TIGR02348; GroEL; 1. DR PROSITE; PS00296; CHAPERONINS_CPN60; 1. KW ATP-binding; Chaperone; Nucleotide-binding. FT CHAIN 1 546 60 kDa chaperonin. FT /FTId=PRO_0000063320. SQ SEQUENCE 546 AA; 57146 MW; 913CD01A5C131A06 CRC64; MAAKDVVFGD SARAKMVEGV NILANAVKVT LGPKGRNVVL ERSFGGPTVT KDGVSVAKEI ELKDKLQNMG AQMVKEVASK TSDNAGDGTT TATVLAQSIV REGMKYVASG MNPMDLKRGI DKAVAAAVEE LKKISKPCTT NKEIAQVGSI SANSDSSIGD RIAEAMDKVG KEGVITVEDG KSLADELDVV EGMQFDRGYL SPYFINNPDK QVAVLENPFV LLHDKKVSNI RDLLPVLEQV AKAGRPLLII AEDVEGEALA TLVVNNIRGI LKTVAVKAPG FGDRRKAMLE DIAILTGGQV IAEETGLTLE KATLAELGQA KRIEVGKENT TIIDGAGEAV NIEARVKQIR TQIEEATSDY DREKLQERVA KLAGGVAVIK VGAATEVEMK EKKARVEDAL HATRAAVEEG IVPGGGVALI RARTAIAALT GVNADQNAGI KIVLRAMEEP LRQIVTNGGE EASVVVAAVA AGKGNYGYNA ATGEYVDMVE AGVVDPTKVT RTALQNAASV AGLLLTTDAA VAELPKEDAP MPGGMPGGMG GMGMDM //