ID   PYRE_METAN     STANDARD;      PRT;   234 AA.
AC   O42767;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   07-FEB-2006, entry version 28.
DE   Orotate phosphoribosyltransferase (EC 2.4.2.10) (OPRT) (OPRTase).
GN   Name=URA5;
OS   Metarhizium anisopliae.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae;
OC   mitosporic Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=5530;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Hwang C.-W., Lee D.-K., Kang S.-C.;
RL   Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Orotidine 5'-phosphate + diphosphate = orotate
CC       + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- PATHWAY: Nucleotide biosynthesis; UMP biosynthesis; UMP from
CC       HCO(3)(-): step 5.
CC   -!- PATHWAY: Context: Pyrimidine biosynthesis.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine
CC       phosphoribosyltransferase family.
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DR   EMBL; AF038545; AAC02431.1; -; Genomic_DNA.
DR   HSSP; P08870; 1LH0.
DR   InterPro; IPR004467; Or_phspho_trans.
DR   InterPro; IPR002375; Pr/py_rp_transf.
DR   InterPro; IPR000836; PRtransferase.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   TIGRFAMs; TIGR00336; pyrE; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
KW   Glycosyltransferase; Transferase.
FT   CHAIN         1    234       Orotate phosphoribosyltransferase.
FT                                /FTId=PRO_0000110798.
FT   ACT_SITE    114    114       By similarity.
SQ   SEQUENCE   234 AA;  25163 MW;  007971EAADD0B253 CRC64;
     MSGQLASYKQ EFLKAAIEGG VLKFGSFELK SKRISPYFFN AGEFHTAHLA GAISSAFAKT
     IIDAQQNAGL DFDIIFGPAY KGIPLCSAIT IKLGEISPQN LDTVSYSFDR KEAKDHGEGG
     NIVGASLKGK KILIVDDVIT AGTAKREAID KIRKEGGIVA GIVVALDRKE KLPAADGDDS
     KPGPSAIGEL RKEYGIPIFA ILTLDDIIAG MKSFASDDDI KRTEEYRQKY KATD
//