ID AMPR_ENTCL STANDARD; PRT; 290 AA. AC P05051; DT 13-AUG-1987 (Rel. 05, Created) DT 01-AUG-1991 (Rel. 19, Last sequence update) DT 05-JUL-2004 (Rel. 44, Last annotation update) DE HTH-type transcriptional activator ampR. GN Name=ampR; OS Enterobacter cloacae. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Enterobacter. OX NCBI_TaxID=550; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=87161784; PubMed=3030737; RA Honore N., Nicolas M.H., Cole S.T.; RT "Inducible cephalosporinase production in clinical isolates of RT Enterobacter cloacae is controlled by a regulatory gene that has been RT deleted from Escherichia coli."; RL EMBO J. 5:3709-3714(1986). CC -!- FUNCTION: This protein is a positive regulator of gene expression CC of cephalosporinase (ampC). CC -!- SUBCELLULAR LOCATION: Cytoplasmic. CC -!- SIMILARITY: Contains 1 HTH lysR-type DNA-binding domain. CC -------------------------------------------------------------------------- CC This Swiss-Prot entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use as long as its content is in no way modified and this statement is not CC removed. CC -------------------------------------------------------------------------- DR EMBL; X04730; CAA28440.1; -. DR PIR; A25686; A25686. DR InterPro; IPR000847; HTH_LysR. DR InterPro; IPR005119; LysR_subst. DR InterPro; IPR009058; Wing_hlx_DNA_bnd. DR Pfam; PF00126; HTH_1; 1. DR Pfam; PF03466; LysR_substrate; 1. DR PRINTS; PR00039; HTHLYSR. DR PROSITE; PS50931; HTH_LYSR; 1. KW Activator; DNA-binding; Transcription regulation. FT INIT_MET 0 0 By similarity. FT DOMAIN 5 62 HTH lysR-type. FT DNA_BIND 22 41 H-T-H motif (By similarity). SQ SEQUENCE 290 AA; 32515 MW; 1F4F35D4AF4EDD64 CRC64; TRSYLPLNSL RAFEAAARHL SFTHAAIELN VTHSAISQHV KTLEQHLNCQ LFVRVSRGLM LTTEGENLLP VLNDSFDRIA GMLDRFANHR AQEKLKIGVV GTFATGVLFS QLEDFRRGYP HIDLQLSTHN NRVDPAAEGL DYTIRYGGGA WHGTEAEFLC HAPLAPLCTP DIAASLHSPA DILRFTLLRS YRRDEWTAWM QAAGEHPPSP THRVMVFDSS VTMLEAAQAG VGIAIAPVDM FTHLLASERI VQPFATQIEL GSYWLTRLQS RAETPAMREF SRWLVEKMKK //