ID   G3P_ENTAE      STANDARD;      PRT;   294 AA.
AC   P24163;
DT   01-MAR-1992 (Rel. 21, Created)
DT   01-MAR-1992 (Rel. 21, Last sequence update)
DT   25-OCT-2004 (Rel. 45, Last annotation update)
DE   Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH)
DE   (Fragment).
GN   Name=gap;
OS   Enterobacter aerogenes (Aerobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=E482;
RX   MEDLINE=92065252; PubMed=1955870;
RA   Lawrence J.G., Ochman H., Hartl D.L.;
RT   "Molecular and evolutionary relationships among enteric bacteria.";
RL   J. Gen. Microbiol. 137:1911-1921(1991).
CC   -!- CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate + phosphate +
CC       NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
CC   -!- PATHWAY: Second phase of glycolysis; first step.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic.
CC   -!- SIMILARITY: Belongs to the glyceraldehyde-3-phosphate
CC       dehydrogenase family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; M63372; AAA24801.1; -.
DR   HSSP; P06977; 1DC5.
DR   InterPro; IPR000173; GAP_dhdrogenase.
DR   InterPro; IPR006424; GAPDH-I.
DR   Pfam; PF02800; Gp_dh_C; 1.
DR   Pfam; PF00044; Gp_dh_N; 1.
DR   PRINTS; PR00078; G3PDHDRGNASE.
DR   TIGRFAMs; TIGR01534; GAPDH-I; 1.
DR   PROSITE; PS00071; GAPDH; FALSE_NEG.
KW   Glycolysis; NAD; Oxidoreductase.
FT   NON_TER       1      1
FT   BINDING     135    135       Glyceraldehyde 3-phosphate.
FT   ACT_SITE    162    162       Activates thiol group during catalysis.
FT   NON_TER     294    294
SQ   SEQUENCE   294 AA;  31448 MW;  F22CA5172621CD8D CRC64;
     IVFRAAQKRS DIEIVGINDL LDAEYMAYML KYDSTHGRFD GTVEVKDGHL VVNGKTIRVT
     AEKDPANLKW NEIGVDVVAE ATGIFLTDET ARKHITAGAK KVVLTGPSKD NTPMFVRGAN
     FETYAGQDIV SNRSCTTNCL APLAKVINDN FGIIEGLMTT VHATTATQKT VDGPSHKDWR
     GGRGAAQNII PSSTGAAKAV GKVLPELNGK LTGMAFRVPT PNVSVVDLTV RLEKAASYEE
     IKKAIKAASE GPMKGVLGYT EDDVVSTDFN GEVCTSVFDA KAGIALNDNF VKLV
//