ID AAC6_ENTAE STANDARD; PRT; 152 AA. AC P50858; DT 01-OCT-1996 (Rel. 34, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 25-OCT-2004 (Rel. 45, Last annotation update) DE Aminoglycoside N(6')-acetyltransferase type 1 (EC 2.3.1.82) (AAC(6')). GN Name=aacA7; OS Enterobacter aerogenes (Aerobacter aerogenes). OG Plasmid pBWH301. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Enterobacter. OX NCBI_TaxID=548; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=95314204; PubMed=7793874; RA Bunny K.L., Hall R.M., Stokes H.W.; RT "New mobile gene cassettes containing an aminoglycoside resistance RT gene, aacA7, and a chloramphenicol resistance gene, catB3, in an RT integron in pBWH301."; RL Antimicrob. Agents Chemother. 39:686-693(1995). CC -!- CATALYTIC ACTIVITY: Acetyl-CoA + kanamycin-B = CoA + N(6')- CC acetylkanamycin-B. CC -------------------------------------------------------------------------- CC This Swiss-Prot entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use as long as its content is in no way modified and this statement is not CC removed. CC -------------------------------------------------------------------------- DR EMBL; U13880; AAA90937.1; -. DR InterPro; IPR000182; GCN5acetyl_trans. DR Pfam; PF00583; Acetyltransf_1; 1. KW Acyltransferase; Antibiotic resistance; Plasmid; Transferase. SQ SEQUENCE 152 AA; 16376 MW; CA2D663D69A867E4 CRC64; MDSSPLVRPV ETTDSASWLS MRCELWPDGT CQEHQSEIAE FLSGKVARPA AVLIAVAPDG EALGFAELSI RPYAEECYSG NVAFLEGWYV VPSARRQGVG VALVKAAEHW ARGRGCTEFA SDTQLTNSAS TSAHLAAGFT EVAQVRCFRK PL //