ID   CAT4_ENTAE     STANDARD;      PRT;   210 AA.
AC   P50868;
DT   01-OCT-1996 (Rel. 34, Created)
DT   01-OCT-1996 (Rel. 34, Last sequence update)
DT   05-JUL-2004 (Rel. 44, Last annotation update)
DE   Chloramphenicol acetyltransferase (EC 2.3.1.28).
GN   Name=catB4;
OS   Enterobacter aerogenes (Aerobacter aerogenes).
OG   Plasmid pBWH301.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=95314204; PubMed=7793874;
RA   Bunny K.L., Hall R.M., Stokes H.W.;
RT   "New mobile gene cassettes containing an aminoglycoside resistance
RT   gene, aacA7, and a chloramphenicol resistance gene, catB3, in an
RT   integron in pBWH301.";
RL   Antimicrob. Agents Chemother. 39:686-693(1995).
CC   -!- FUNCTION: This enzyme is an effector of chloramphenicol resistance
CC       in bacteria.
CC   -!- CATALYTIC ACTIVITY: Acetyl-CoA + chloramphenicol = CoA +
CC       chloramphenicol 3-acetate.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; U13880; AAA90938.1; -.
DR   HSSP; P26841; 2XAT.
DR   InterPro; IPR001451; Hexapep_transf.
DR   InterPro; IPR011004; Trimer_LpxA_like.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
KW   Acyltransferase; Antibiotic resistance; Plasmid; Repeat; Transferase.
FT   ACT_SITE     79     79       By similarity.
SQ   SEQUENCE   210 AA;  23617 MW;  25422E5C0A15BF64 CRC64;
     MTNYFDSPFK GKLLSEQVKN PNIKVGRYSY YSGYYHGHSF DDCARYLFPD RDDVDKLIIG
     SFCSIGSGAS FIMAGNQGHR YDWASSFPFF YMQEEPAFSS ALDAFQKAGN TVIGNDVWIG
     SEAMVMPGIK IGHGAVIGSR SLVTKDVEPY AIVGGNPAKK IKKRFTDEEI SLLLEMEWWN
     WSLEKIKAAM PMLCSSNIVG LHKYWLEFAV
//