LOCUS       AF395881                 960 bp    DNA     linear   BCT 29-NOV-2004
DEFINITION  Klebsiella pneumoniae carbapenem-hydrolyzing beta-lactamase KPC-3
            (bla) gene, complete cds.
ACCESSION   AF395881
VERSION     AF395881.1  GI:15705412
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Klebsiella.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Woodford,N., Tierno,P.M. Jr., Young,K., Tysall,L., Palepou,M.F.,
            Ward,E., Painter,R.E., Suber,D.F., Shungu,D., Silver,L.L.,
            Inglima,K., Kornblum,J. and Livermore,D.M.
  TITLE     Outbreak of Klebsiella pneumoniae Producing a New Carbapenem-
            Hydrolyzing Class A {beta}-Lactamase, KPC-3, in a New York Medical
            Center
  JOURNAL   Antimicrob. Agents Chemother. 48 (12), 4793-4799 (2004)
   PUBMED   15561858
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Tysall,L., Palepou,M.F., Livermore,D.M. and Woodford,N.
  TITLE     KPC-3, a carbapenem-hydrolyzing beta-lactamase from Klebsiella
            pneumoniae
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 960)
  AUTHORS   Tysall,L., Palepou,M.F., Livermore,D.M. and Woodford,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2001) ARMRL, CPHL, 61 Colindale Avenue, London
            NW9 5HT, UK
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="CL-5761"
                     /db_xref="taxon:573"
     gene            1..882
                     /gene="bla"
     CDS             1..882
                     /gene="bla"
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing beta-lactamase KPC-3"
                     /protein_id="AAL05630.1"
                     /db_xref="GI:15705413"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSI
                     GVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALV
                     PWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFR
                     LDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNH
                     RIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKYSEAV
                     IAAAARLALEGLGVNGQ"
ORIGIN      
        1 atgtcactgt atcgccgtct agttctgctg tcttgtctct catggccgct ggctggcttt
       61 tctgccaccg cgctgaccaa cctcgtcgcg gaaccattcg ctaaactcga acaggacttt
      121 ggcggctcca tcggtgtgta cgcgatggat accggctcag gcgcaactgt aagttaccgc
      181 gctgaggagc gcttcccact gtgcagctca ttcaagggct ttcttgctgc cgctgtgctg
      241 gctcgcagcc agcagcaggc cggcttgctg gacacaccca tccgttacgg caaaaatgcg
      301 ctggttccgt ggtcacccat ctcggaaaaa tatctgacaa caggcatgac ggtggcggag
      361 ctgtccgcgg ccgccgtgca atacagtgat aacgccgccg ccaatttgtt gctgaaggag
      421 ttgggcggcc cggccgggct gacggccttc atgcgctcta tcggcgatac cacgttccgt
      481 ctggaccgct gggagctgga gctgaactcc gccatcccag gcgatgcgcg cgatacctca
      541 tcgccgcgcg ccgtgacgga aagcttacaa aaactgacac tgggctctgc actggctgcg
      601 ccgcagcggc agcagtttgt tgattggcta aagggaaaca cgaccggcaa ccaccgcatc
      661 cgcgcggcgg tgccggcaga ctgggcagtc ggagacaaaa ccggaacctg cggagtgtat
      721 ggcacggcaa atgactatgc cgtcgtctgg cccactgggc gcgcacctat tgtgttggcc
      781 gtctacaccc gggcgcctaa caaggatgac aagtacagcg aggccgtcat cgccgctgcg
      841 gctagactcg cgctcgaggg attgggcgtc aacgggcagt aaggctctga aaatcatcta
      901 ttggcccacc accgccgccc ttgcgggcgg catggattac caaccactgt cacatttagg
//