ID   ALDC_ENTAE     STANDARD;      PRT;   260 AA.
AC   P05361; Q59340;
DT   01-NOV-1988 (Rel. 09, Created)
DT   01-NOV-1988 (Rel. 09, Last sequence update)
DT   01-FEB-2005 (Rel. 46, Last annotation update)
DE   Alpha-acetolactate decarboxylase (EC 4.1.1.5).
GN   Name=budA; Synonyms=aldC;
OS   Enterobacter aerogenes (Aerobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=88149041; PubMed=3278689;
RA   Sone H., Fujii T., Kondo K., Shimizu F., Tanaka J.-I., Inoue T.;
RT   "Nucleotide sequence and expression of the Enterobacter aerogenes
RT   alpha-acetolactate decarboxylase gene in brewer's yeast.";
RL   Appl. Environ. Microbiol. 54:38-42(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8444801;
RA   Blomqvist K., Nikkola M., Lehtovaara P., Suihko M.L., Airaksinen U.,
RA   Straby K.B., Knowles J.K., Penttila M.E.;
RT   "Characterization of the genes of the 2,3-butanediol operons from
RT   Klebsiella terrigena and Enterobacter aerogenes.";
RL   J. Bacteriol. 175:1392-1404(1993).
CC   -!- FUNCTION: Converts acetolactate into acetoin, which can be
CC       excreted by the cells. This may be a mechanism for controlling the
CC       internal pH of cells in the stationary stage.
CC   -!- CATALYTIC ACTIVITY: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-
CC       acetoin + CO(2).
CC   -!- PATHWAY: Acetoin biosynthesis.
CC   -!- SIMILARITY: Belongs to the alpha-acetolactate decarboxylase
CC       family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; J03433; AAA24794.1; -.
DR   EMBL; L04506; AAA56801.1; -.
DR   PIR; A32515; A32515.
DR   InterPro; IPR005128; Acetolac_decarb.
DR   Pfam; PF03306; AAL_decarboxy; 1.
DR   PIRSF; PIRSF001332; Acetolac_decarb; 1.
DR   ProDom; PD006931; Acetolac_decarb; 1.
DR   TIGRFAMs; TIGR01252; acetolac_decarb; 1.
KW   Acetoin biosynthesis; Decarboxylase; Lyase.
FT   CONFLICT     24     24       K -> Q (in Ref. 2).
FT   CONFLICT     45     47       EGD -> VGE (in Ref. 2).
FT   CONFLICT    113    114       DA -> NG (in Ref. 2).
FT   CONFLICT    137    138       AL -> V (in Ref. 2).
FT   CONFLICT    257    257       S -> A (in Ref. 2).
SQ   SEQUENCE   260 AA;  29032 MW;  BDDC14B941E012F3 CRC64;
     MMMHSSACDC EASLCETLRG FSAKHPDSVI YQTSLMSALL SGVYEGDTTI ADLLAHGDFG
     LGTFNELDGE MIAFSSQVYQ LRADGSARAA KPEQKTPFAV MTWFQPQYRK TFDAPVSRQQ
     IHDVIDQQIP SDNLFCALRI DGNFRHAHTR TVPRQTPPYR AMTDVLDDQP VFRFNQREGV
     LVGFRTPQHM QGINVAGYHE HFITDDRQGG GHLLDYQLES GVLTFGEIHK LMIDLPADSA
     FLQANLHPSN LDAAIRSVEN
//