ID   ARS_KLEAE      STANDARD;      PRT;   464 AA.
AC   P20713;
DT   01-FEB-1991 (Rel. 17, Created)
DT   01-FEB-1991 (Rel. 17, Last sequence update)
DT   05-JUL-2004 (Rel. 44, Last annotation update)
DE   Arylsulfatase precursor (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase).
GN   Name=atsA;
OS   Klebsiella aerogenes.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=28451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE, AND PROTEIN SEQUENCE OF 21-33.
RX   MEDLINE=90202736; PubMed=2180918;
RA   Murooka Y., Ishibashi K., Yasumoto M., Sasaki M., Sugino H.,
RA   Azakami H., Yamashita M.;
RT   "A sulfur- and tyramine-regulated Klebsiella aerogenes operon
RT   containing the arylsulfatase (atsA) gene and the atsB gene.";
RL   J. Bacteriol. 172:2131-2140(1990).
CC   -!- FUNCTION: As is commonly produced by soil microorganisms and plays
CC       an important role in the mineralization of sulfates.
CC   -!- CATALYTIC ACTIVITY: A phenol sulfate + H(2)O = a phenol + sulfate.
CC   -!- COFACTOR: Binds 1 calcium ion per subunit (By similarity).
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
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DR   EMBL; M31938; AAA25051.1; -.
DR   PIR; B35159; B35159.
DR   HSSP; P15289; 1E33.
DR   InterPro; IPR000917; Sulfatase.
DR   Pfam; PF00884; Sulfatase; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
KW   Calcium-binding; Direct protein sequencing; Hydrolase; Metal-binding;
KW   Signal.
FT   SIGNAL        1     20
FT   CHAIN        21    464       Arylsulfatase.
FT   MOD_RES      72     72       3-oxoalanine (Ser) (By similarity).
FT   ACT_SITE    134    134       By similarity.
FT   METAL        34     34       Calcium (By similarity).
FT   METAL        35     35       Calcium (By similarity).
FT   METAL        50     50       Calcium (via 3-oxoalanine).
FT   METAL       329    329       Calcium (By similarity).
FT   METAL       330    330       Calcium (By similarity).
SQ   SEQUENCE   464 AA;  51471 MW;  C8D09AB9EEF9C627 CRC64;
     MNKKAMAAAV SMILAGGAHA AQQERPNVIV IIADDMGYSD ISPFGGEIPT PNLQAMAEQG
     MRMSQYYTSP MSAPARSMLL TGNSNQQAGM GGMWWYDSTI GKEGYELRLT DRVTTMAERF
     KDAGYNTLMA GKWHLGFVPG ATPKDRGFNH AFAFMGGGTS HFNDAIPLGT VEAFHTYYTR
     DGERVSLPDD FYSSEAYARQ MNSWIKATPK EQPVFAWLAF TAPHDPLQAP DEWIKRFKGQ
     YEQGYAEVYR QRIARLKALG IIHDDTPLPH LELDKEWEAL TPEQQKYTAK VMQVYAAMIA
     NMDAQIGTLM ETLKQTGRDK NTLLVFLTDN GANPAQGFYY ESTPEFWKQF DNSYDNVGRK
     GSFVSYGPHW ANVSNAPYAN YHKTTSAQGG INTDFMISGP GITRHGKIDA STMAVYDVAP
     TLYEFAGIDP NKSLAKKPVL PMIGVSLSAI SPAKYRSRRA ELRG
//