ID   DPOL_NPVAC     STANDARD;      PRT;   984 AA.
AC   P18131;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   21-MAR-2006, entry version 34.
DE   DNA polymerase (EC 2.7.7.7).
GN   Name=POL;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; dsDNA viruses, no RNA stage; Baculoviridae;
OC   Nucleopolyhedrovirus.
OX   NCBI_TaxID=46015;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=L1;
RX   MEDLINE=89073763; PubMed=3059678;
RA   Tomalski M.D., Wu J.G., Miller L.K.;
RT   "The location, sequence, transcription, and regulation of a
RT   baculovirus DNA polymerase gene.";
RL   Virology 167:591-600(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   MEDLINE=94303173; PubMed=8030224;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear
RT   polyhedrosis virus.";
RL   Virology 202:586-605(1994).
CC   -!- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) =
CC       diphosphate + DNA(n+1).
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
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DR   EMBL; M20744; AAA46692.1; -; Genomic_DNA.
DR   EMBL; L22858; AAA66695.1; -; Genomic_DNA.
DR   PIR; A31832; DJNVCP.
DR   InterPro; IPR006172; DNA_pol_B.
DR   InterPro; IPR006133; DNA_pol_B_exo.
DR   InterPro; IPR006134; DNA_pol_B_region.
DR   InterPro; IPR012337; RNaseH_fold.
DR   Pfam; PF00136; DNA_pol_B; 2.
DR   Pfam; PF03104; DNA_pol_B_exo; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
KW   DNA replication; DNA-binding; DNA-directed DNA polymerase;
KW   Early protein; Nucleotidyltransferase; Transferase.
FT   CHAIN         1    984       DNA polymerase.
FT                                /FTId=PRO_0000046526.
FT   COMPBIAS    724    727       Poly-Lys.
FT   COMPBIAS    946    960       Poly-Asp.
FT   CONFLICT    830    830       R -> W (in Ref. 1).
SQ   SEQUENCE   984 AA;  114308 MW;  156ABB6BA1B45A21 CRC64;
     MKIYPYNELK TRFAEYAKPG EFNITSADTF RIIRLHYDEK QGCLFAFCNT NIKERVLQFY
     FKVKLNLYSY KQCYDKHIFP SCRNKCISYT TFVAPGVEGN YLNKINVIKY ERNKAAPSDN
     AACLDKFLHN VNRVHMQTPF VEGAYMRFKK TQRCQNNYVG GSTTRMFNLQ HFNEDFELVD
     EMTLTSGIMP VLSCYDIETH SDGHNMSKAS VDCIMSIGFV VYKNDEYAKF CFMYHKLPTQ
     IPETYDDDTY VVMFQNEIDM ITAFFDMIKI TNPDVILDFN GDVFDLPYIL GRLNKTKMLL
     KRYDLPAAAP TTKLFINKLG NKVDTYYFNY YIHIDLYKFF SSDSNQHKVE NFQLNTISSY
     YLGENKIDLP WTEMVKMYNT RRLDVIAKYN VQDCMLPIKL FVKLKMADSV YSQCILHRLC
     TDDVICNISH LISVACFYAA ITNTRINEST GKEEPDPYFF NKNDLSIISG QFKADKAAAG
     ISNLKRKLIP LKNIPKDAIN LGPANQTVKY KGGKVLKPRA GIYKNAFSLD FNSLYLTIMI
     AICACLSNLI LCEDGNVYLN HNSRAIVVKL LLKLLSERCK FKKNRDNQSE SAFLYDLYDQ
     KQNSVKRTAN SIYGYYGIFY KVLANYITRV GRNQLRLAIS LIEGLSNDPE ILEKFNLGSI
     TFKVVYGDTD STFVLPTFNY NEISNETDTL KQICTHVETR VNNSFTDGYK MAFENLMKVL
     ILLKKKKYCY LNSENKIVYK GWLVKKDMPV FMRIAFRTAV EQILRHLDMD KCLQSLQTSF
     YEYYDEFAKS KSLTDYSFSM TYNDNPGKKR KSTDDNEGPS PKRRVITVAR HCREILVNKG
     TDFVPGNGDR IPYLLIDIEG KVTEKAYPLR LFDPVKMRIS WIKHMGILCT FMNELLEIFG
     DEQKDKIAKC FTAIMQKYMQ NQLYDRKEPV LVKINQKKCS VKRKRDDDDD NDDDDDDDCD
     SSDSENDTQC ANNTYKFCLY KMKK
//