ID HYDA_BURPI STANDARD; PRT; 457 AA. AC Q8VTT5; DT 06-JUN-2002, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2002, sequence version 1. DT 21-MAR-2006, entry version 29. DE D-hydantoinase (EC 3.5.2.2) (Dihydropyrimidinase) (DHPase). OS Burkholderia pickettii (Ralstonia pickettii) (Pseudomonas pickettii). OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; OC Burkholderiaceae; Ralstonia. OX NCBI_TaxID=329; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Xu Z., Jiang W.-H., Yang Y.-L.; RT "Cloning, sequencing and expression of a hydantoinase gene of RT Burholderia pickettii."; RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: 5,6-dihydrouracil + H(2)O = CC 3-ureidopropanoate. CC -!- SIMILARITY: Belongs to the dehydropyrimidinase family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF320814; AAL37185.1; -; Genomic_DNA. DR PDB; 1NFG; X-ray; A/B/C/D=1-457. DR InterPro; IPR006680; Amidohydro_1. DR InterPro; IPR011778; D-hydantoinase. DR InterPro; IPR005847; DHOase. DR InterPro; IPR011059; Metalo_hydrolase. DR Pfam; PF01979; Amidohydro_1; 1. DR ProDom; PD000518; DHOase; 1. DR TIGRFAMs; TIGR02033; D-hydantoinase; 1. KW 3D-structure; Hydrolase. FT CHAIN 1 457 D-hydantoinase. FT /FTId=PRO_0000165934. FT STRAND 3 12 FT TURN 13 14 FT STRAND 15 24 FT TURN 25 26 FT STRAND 27 33 FT STRAND 39 43 FT TURN 45 46 FT STRAND 48 51 FT STRAND 53 58 FT STRAND 61 61 FT STRAND 63 64 FT TURN 65 66 FT STRAND 67 68 FT STRAND 70 70 FT HELIX 73 82 FT TURN 83 84 FT STRAND 85 93 FT TURN 96 97 FT STRAND 98 98 FT HELIX 100 111 FT TURN 112 114 FT STRAND 116 124 FT STRAND 126 127 FT HELIX 130 135 FT TURN 136 138 FT HELIX 139 142 FT TURN 143 143 FT STRAND 146 153 FT TURN 154 157 FT STRAND 158 158 FT HELIX 161 174 FT TURN 175 175 FT STRAND 177 181 FT HELIX 185 197 FT TURN 198 199 FT STRAND 202 202 FT TURN 203 203 FT HELIX 204 208 FT TURN 209 209 FT STRAND 210 210 FT HELIX 212 229 FT TURN 230 230 FT STRAND 233 235 FT STRAND 240 240 FT HELIX 241 253 FT TURN 254 254 FT STRAND 257 259 FT STRAND 261 262 FT HELIX 263 266 FT TURN 267 267 FT HELIX 270 274 FT TURN 276 278 FT HELIX 279 283 FT STRAND 286 287 FT HELIX 292 303 FT TURN 304 305 FT STRAND 308 308 FT STRAND 310 311 FT STRAND 314 314 FT TURN 319 328 FT HELIX 330 332 FT STRAND 333 333 FT STRAND 337 337 FT TURN 340 342 FT HELIX 343 352 FT TURN 353 354 FT STRAND 355 356 FT HELIX 358 365 FT TURN 366 366 FT HELIX 367 372 FT TURN 373 374 FT TURN 376 378 FT STRAND 379 381 FT STRAND 383 383 FT TURN 384 385 FT STRAND 386 387 FT STRAND 390 400 FT HELIX 403 405 FT STRAND 406 406 FT STRAND 408 409 FT STRAND 411 411 FT TURN 414 417 FT STRAND 419 429 FT TURN 430 431 FT STRAND 432 436 FT TURN 437 438 FT STRAND 439 440 FT TURN 444 445 FT STRAND 446 446 FT STRAND 449 449 FT STRAND 454 454 SQ SEQUENCE 457 AA; 49932 MW; 1DC2301D2A9E276E CRC64; MDIIIKNGTI VTADGISRAD LGIKDGKITQ IGGALGPAER TIDAAGRYVF PGGIDVHTHV ETVSFNTQSA DTFATATVAA ACGGTTTIVD FCQQDRGHSL AEAVAKWDGM AGGKSAIDYG YHIIVLDPTD SVIEELEVLP DLGITSFKVF MAYRGMNMID DVTLLKTLDK AVKTGSLVMV HAENGDAADY LRDKFVAEGK TAPIYHALSR PPRVEAEATA RALALAEIVN APIYIVHVTC EESLEEVMRA KSRGVRALAE TCTHYLYLTK EDLERPDFEG AKYVFTPPAR AKKDHDVLWN ALRNGVFETV SSDHCSWLFK GHKDRGRNDF RAIPNGAPGV EERLMMVYQG VNEGRISLTQ FVELVATRPA KVFGMFPQKG TIAVGSDADI VLWDPEAEMV IEQTAMHNAM DYSSYEGHKV KGVPKTVLLR GKVIVDEGSY VGEPTDGKFL KRRKYKQ //