ID   CYSA_BURCE     STANDARD;      PRT;   264 AA.
AC   Q93DX8;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   07-MAR-2006, entry version 23.
DE   Sulfate/thiosulfate import ATP-binding protein cysA (EC 3.6.3.25)
DE   (Sulfate-transporting ATPase) (Fragment).
GN   Name=cysA;
OS   Burkholderia cepacia (Pseudomonas cepacia).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=14702294; DOI=10.1128/JB.186.2.270-277.2004;
RA   Farmer K.L., Thomas M.S.;
RT   "Isolation and characterization of Burkholderia cenocepacia mutants
RT   deficient in pyochelin production: pyochelin biosynthesis is sensitive
RT   to sulfur availability.";
RL   J. Bacteriol. 186:270-277(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex cysAWTP involved in
CC       sulfate/thiosulfate import. Responsible for energy coupling to the
CC       transport system (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O + sulfate(Out) = ADP + phosphate +
CC       sulfate(In).
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (cysA), two transmembrane proteins (cysT and cysW) and a solute-
CC       binding protein (cysP) (Probable).
CC   -!- SUBCELLULAR LOCATION: Bacterial cell inner membrane; peripheral
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the ABC transporter family.
CC       Sulfate/tungstate importer (TC 3.A.1.6) subfamily.
CC   -!- SIMILARITY: Contains 1 ABC transporter domain.
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DR   EMBL; AF374458; AAL13241.1; -; Genomic_DNA.
DR   InterPro; IPR003593; AAA_ATPase.
DR   InterPro; IPR003439; ABC_transp_like.
DR   InterPro; IPR000803; Gluc_transporter.
DR   InterPro; IPR005666; Sulph_transpt1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   PRINTS; PR00172; GLUCTRNSPORT.
DR   ProDom; PD000006; ABC_transporter; 1.
DR   SMART; SM00382; AAA; 1.
DR   TIGRFAMs; TIGR00968; 3a0106s01; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
KW   ATP-binding; Hydrolase; Inner membrane; Membrane; Nucleotide-binding;
KW   Sulfate transport; Transport.
FT   CHAIN         1   >264       Sulfate/thiosulfate import ATP-binding
FT                                protein cysA.
FT                                /FTId=PRO_0000092259.
FT   DOMAIN        3    237       ABC transporter.
FT   NP_BIND      35     42       ATP (By similarity).
FT   NON_TER     264    264
SQ   SEQUENCE   264 AA;  29138 MW;  95FCB1084BF637FE CRC64;
     MGITVRNLQK RFGDFTALDN VSLDFPPGEL VALLGPSGCG KTTLLRVIAG LEHADAGQVV
     LQGLDVASVG ARDRQVGFVF QHYALFRHMT VFENVAFGLR VKPRRERPSE AAIREKVHEL
     LKLVQLDWLA QRYPSELSGG QRQRIALARA LAVEPKVLLL DEPFGALDAK VRKELRGWLR
     RLHDDLHIST IFVTHDQEEA LEVADRIVVL NRGHVEQVGS PQDVYDHPQS AFVYEFLGAA
     NRLPGTVAGR GFVAEGAAAP TEVD
//