ID OSTL_PLEOS STANDARD; PRT; 50 AA. AC P83467; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 05-JUL-2004 (Rel. 44, Last annotation update) DE Ostreolysin (Fragment). OS Pleurotus ostreatus (Oyster mushroom) (White-rot fungus). OC Eukaryota; Fungi; Basidiomycota; Hymenomycetes; Homobasidiomycetes; OC Agaricales; Pleurotaceae; Pleurotus. OX NCBI_TaxID=5322; RN [1] RP PROTEIN SEQUENCE, FUNCTION, SUBUNIT, AND DEVELOPMENTAL STAGE. RC STRAIN=Plo 5; TISSUE=Fruiting body; RX MEDLINE=22015236; PubMed=12020804; DOI=10.1016/S0304-4165(02)00190-3; RA Berne S., Krizaj I., Pohleven F., Turk T., Macek P., Sepcic K.; RT "Pleurotus and Agrocybe hemolysins, new proteins hypothetically RT involved in fungal fruiting."; RL Biochim. Biophys. Acta 1570:153-159(2002). CC -!- FUNCTION: Has hemolytic activity against bovine erythrocytes at CC nanomolar concentrations. May play an important role in the CC initial phase of fungal fruiting. CC -!- SUBUNIT: Monomer. CC -!- DEVELOPMENTAL STAGE: Expression begins during formation of the CC primordia, increases remarkably as the fruiting bodies develop and CC declines as they mature. CC -!- SIMILARITY: Belongs to the aegerolysin family. DR InterPro; IPR009413; Aegerolysin. DR Pfam; PF06355; Aegerolysin; 1. KW Direct protein sequencing; Hemolysis. FT DOMAIN 7 10 Poly-Ile. FT NON_TER 50 50 SQ SEQUENCE 50 AA; 5495 MW; DF3C7B9DE7D7448F CRC64; AYAQWVIIII HNVGSQDVKI KNLKASWGKL HADGDKDAEV SASNYEGKII //