ID O86984_THEFU PRELIMINARY; PRT; 368 AA. AC O86984; DT 01-NOV-1998 (TrEMBLrel. 08, Created) DT 01-NOV-1998 (TrEMBLrel. 08, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE Alkaline serine protease precursor. OS Thermomonospora fusca. OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Streptosporangineae; Nocardiopsaceae; Thermobifida. OX NCBI_TaxID=2021; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=YX; RX MEDLINE=97055734; PubMed=8900021; RA Lao G., Wilson D.B.; RT "Cloning, sequencing, and expression of a Thermomonospora fusca RT protease gene in Streptomyces lividans."; RL Appl. Environ. Microbiol. 62:4256-4259(1996). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=YX; RA Lao G., Wilson D.B.; RL Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases. DR EMBL; U65895; AAC23545.1; -. DR HSSP; P00778; 1GBJ. DR GO; GO:0005576; C:extracellular region; IEA. DR GO; GO:0004295; F:trypsin activity; IEA. DR GO; GO:0006508; P:proteolysis and peptidolysis; IEA. DR InterPro; IPR001254; Peptidase_S1. DR InterPro; IPR004236; Pept_alpha_lytic. DR InterPro; IPR001316; Pept_S1E_Alytic. DR Pfam; PF02983; Pro_Al_protease; 1. DR Pfam; PF00089; Trypsin; 1. DR PRINTS; PR00861; ALYTICPTASE. DR PROSITE; PS00135; TRYPSIN_SER; UNKNOWN_1. KW Hydrolase; Protease; Serine protease; Signal. FT SIGNAL 1 31 Potential. FT CHAIN 181 368 alkaline serine protease. SQ SEQUENCE 368 AA; 38031 MW; 69CBACB8F15B2DEA CRC64; MNHSSRRTTS LLFTAALAAT ALVAATTPAS AQELALKRDL GLSDAEVAEL RAAEAEAVEL EEELRDSLGS DFGGVYLDAD TTEITVAVTD PAAVSRVDAD DVTVDVVDFG ETALNDFVAS LNAIADTADP KVTGWYTDLE SDAVVITTLR GGTPAAEELA ERAGLDERAV RIVEEDEEPQ SLAAIIGGNP YYFGNYRCSI GFSVRQGSQT GFATAGHCGS TGTRVSSPSG TVAGSYFPGR DMGWVRITSA DTVTPLVNRY NGGTVTVTGS QEAATGSSVC RSGATTGWRC GTIQSKNQTV RYAEGTVTGL TRTTACAEGG DSGGPWLTGS QAQGVTSGGT GDCRSGGITF FQPINPLLSY FGLQLVTG //