ID   Q08166_THEFU PRELIMINARY;      PRT;   974 AA.
AC   Q08166;
DT   01-NOV-1996 (TrEMBLrel. 01, Created)
DT   01-NOV-1996 (TrEMBLrel. 01, Last sequence update)
DT   01-MAR-2004 (TrEMBLrel. 26, Last annotation update)
DE   Beta-1,4-endoglucanase precursor.
OS   Thermomonospora fusca.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptosporangineae; Nocardiopsaceae; Thermobifida.
OX   NCBI_TaxID=2021;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX;
RX   MEDLINE=91258320; PubMed=1904434;
RA   Lao G., Ghangas G.S., Jung E.D., Wilson D.B.;
RT   "DNA sequences of three beta-1,4-endoglucanase genes from
RT   Thermomonospora fusca.";
RL   J. Bacteriol. 173:3397-3407(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX;
RA   Lin E., Wilson D.B.;
RT   "Identification of a celE binding protein and its potential role in
RT   induction of the celE gene in Thermomonospora fusca.";
RL   J. Bacteriol. 1701:3843-3846(1988).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX;
RA   Irwin D.C., Spezio M., Walker L.P., Wilson D.B.;
RT   "Activity studies of eight purified cellulases: specificty, synergism,
RT   and binding domain effects.";
RL   Biotechnol. Bioeng. 42:1002-1013(1993).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX;
RX   MEDLINE=94028932; PubMed=8215374;
RA   Jung E.D., Lao G., Irwin D., Barr B.K., Benjamin A., Wilson D.B.;
RT   "DNA sequences and expression in Streptomyces lividans of an
RT   exoglucanase gene and an endoglucanase gene from Thermomonospora
RT   fusca.";
RL   Appl. Environ. Microbiol. 59:3032-3043(1993).
DR   EMBL; L20094; AAC06387.1; -.
DR   HSSP; P20533; 1K85.
DR   GO; GO:0008810; F:cellulase activity; IEA.
DR   GO; GO:0005975; P:carbohydrate metabolism; IEA.
DR   InterPro; IPR001919; Bac_celose-bind.
DR   InterPro; IPR003305; CBM_CenC.
DR   InterPro; IPR003961; FN_III.
DR   InterPro; IPR001701; Glyco_hydro_9.
DR   InterPro; IPR004197; Glyco_hydro_9Ig.
DR   InterPro; IPR002345; Lipocalin.
DR   Pfam; PF00553; CBM_2; 1.
DR   Pfam; PF02018; CBM_4_9; 1.
DR   Pfam; PF02927; CelD_N; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF00759; Glyco_hydro_9; 1.
DR   SMART; SM00637; CBD_II; 1.
DR   SMART; SM00060; FN3; 1.
DR   PROSITE; PS50853; FN3; 1.
DR   PROSITE; PS00698; GLYCOSYL_HYDROL_F9_2; 1.
DR   PROSITE; PS00213; LIPOCALIN; UNKNOWN_1.
KW   Signal.
FT   SIGNAL        1     32       Potential.
FT   CHAIN        33    974       beta-1,4-endoglucanase.
SQ   SEQUENCE   974 AA;  104577 MW;  17FEE7330404A83C CRC64;
     MLRRPRSRSP LVALTAATCR VALGGTAVPA QADEVNQIRN GDFSSGTAPW WGTENIQLNV
     TDGMLCVDVP GGTVNPWDVI IGQDDIPLIE GESYAFSFTA SSTVPVSIRA LVQEPVEPWT
     TQMDERALLG PEAETYEFVF TSNVDWDDAQ VAFQIGGSDE PWTFCLDDVA LLGRAEPPVY
     EPDTGPRVRV NQVGYLPHGP KKATVVTDAT SALTWELADA DGNVVASGQT KPHGADSSSG
     LNVHTVDFSS YTTKGSDYTL TVDGETSYPF DIDESVYEEL RVDALSFYYP QRSGIEILDS
     IAPGYGRPAG HIGVPPNQGD TDVPCAPGTC DYSLDVSGGW YDAGDHGKYV VNGGISVHQI
     MSIYERSQLA DTAQPDKLAD STLRLPETGN GVPDVLDEAR WEMEFLLKMQ VPEGEPLAGM
     AHHKIHDEQW TGLPLLPSAD PQPRYLQPPS TAATLNLAAT AAQCARVFEP FDEDFAAECL
     AAAETAWDAA KANPNIYAPA FGEGGGPYND NNVTDEFYWA AAELFLTTGK EEYRDAVTSS
     PLHTDDEEVF RDGAFDWGWT AALARLQLAT IPNDLADRDR VRQSVVDAAD MYLANVETSP
     WGLAYKPNNG VFVWGSNSAV LNNMVILAVA FDLTGDTKYR DGVLEGMDYI FGRNALNQSY
     VTGYGDKDSR NQHSRWYAHQ LDPRLPNPPK GTLAGGPNSD STTWDPVAQS KLTGCAPQMC
     YIDHIESWST NELTINWNAP LSWIASFIAD QDDAGEPGGE EPGPGDDETP PSKPGNLKAS
     DITATSATLT WDASTDNVGV VGYKVSLVRD GDAEEVGTTA QTSYTLTGLS ADQEYTVQVV
     AYDAAGNLST PATVTFTTEK EDETPTPSAS CAVTYQTNDW PGGFTASVTL TNTGSTPWDS
     WELRFTFPSG QTVSHGWSAN WQQSGSDVTA TSLPWNGSVP PGGGSVNIGF NGTWGGSNTK
     PEKFTVNGAV CSIG
//