ID   Q60029_THEFU PRELIMINARY;      PRT;   596 AA.
AC   Q60029;
DT   01-NOV-1996 (TrEMBLrel. 01, Created)
DT   01-NOV-1996 (TrEMBLrel. 01, Last sequence update)
DT   01-OCT-2003 (TrEMBLrel. 25, Last annotation update)
DE   Beta-1,4-exocellulase precursor (EC 3.2.1.91).
OS   Thermomonospora fusca.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Streptosporangineae; Nocardiopsaceae; Thermobifida.
OX   NCBI_TaxID=2021;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX;
RX   MEDLINE=95186496; PubMed=7880834;
RA   Zhang S., Lao G., Wilson D.B.;
RT   "Characterization of a Thermomonospora fusca exocellulase.";
RL   Biochemistry 34:3386-3395(1995).
CC   -!- CATALYTIC ACTIVITY: Endohydrolysis of 1,4-beta-D-glucosidic
CC       linkages in cellulose, lichenin and cereal beta-D-glucans.
DR   EMBL; U18978; AAA62211.1; -.
DR   PIR; A55976; A55976.
DR   HSSP; P07986; 1EXG.
DR   GO; GO:0016162; F:cellulose 1,4-beta-cellobiosidase activity; IEA.
DR   GO; GO:0005975; P:carbohydrate metabolism; IEA.
DR   GO; GO:0030245; P:cellulose catabolism; IEA.
DR   GO; GO:0000272; P:polysaccharide catabolism; IEA.
DR   InterPro; IPR001919; Bac_celose-bind.
DR   InterPro; IPR001524; Glyco_hydro_6.
DR   InterPro; IPR006311; Tat.
DR   Pfam; PF00553; CBM_2; 1.
DR   Pfam; PF01341; Glyco_hydro_6; 1.
DR   PRINTS; PR00733; GLHYDRLASE6.
DR   ProDom; PD003733; Glyco_hydro_6; 1.
DR   SMART; SM00637; CBD_II; 1.
DR   TIGRFAMs; TIGR01409; TAT_signal_seq; 1.
DR   PROSITE; PS00655; GLYCOSYL_HYDROL_F6_1; 1.
KW   Carbohydrate metabolism; Cellulose degradation; Glycosidase;
KW   Hydrolase; Polysaccharide degradation; Signal.
FT   SIGNAL        1     38       Potential.
FT   CHAIN        39    596       beta-1,4-exocellulase.
SQ   SEQUENCE   596 AA;  63547 MW;  B0FA5277FE7721E0 CRC64;
     MSKVRATNRR SWMRRGLAAA SGLALGASMV AFAAPANAAG CSVDYTVNSW GTGFTANVTI
     TNLGSAINGW TLEWDFPGNQ QVTNLWNGTY TQSGQHVSVS NAPYNASIPA NGTVEFGFNG
     SYSGSNDIPS SFKLNGVTCD GSDDPDPEPS PSPSPSPSPT DPDEPGGPTN PPTNPGEKVD
     NPFEGAKLYV NPVWSAKAAA EPGGSAVANE STAVWLDRIG AIEGNDSPTT GSMGLRDHLE
     EAVRQSGGDP LTIQVVIYNL PGRDCAALAS NGELGPDELD RYKSEYIDPI ADIMWDFADY
     ENLRIVAIIE IDSLPNLVTN VGGNGGTELC AYMKQNGGYV NGVGYALRKL GEIPNVYNYI
     DAAHHGWIGW DSNFGPSVDI FYEAANASGS TVDYVHGFIS NTANYSATVE PYLDVNGTVN
     GQLIRQSKWV DWNQYVDELS FVQDLRQALI AKGFRSDIGM LIDTSRNGWG GPNRPTGPSS
     STDLNTYVDE SRIDRRIHPG NWCNQAGAGL GERPTVNPAP GVDAYVWVKP PGESDGASEE
     IPNDEGKGFD RMCDPTYQGN ARNGNNPSGA LPNAPISGHW FSAQFRELLA NAYPPL
//