LOCUS AY328083 4494 bp mRNA linear PLN 02-DEC-2004 DEFINITION Hypocrea jecorina serine/threonine kinase IREI mRNA, complete cds. ACCESSION AY328083 VERSION AY328083.1 GI:33087515 KEYWORDS . SOURCE Hypocrea jecorina (anamorph: Trichoderma reesei) ORGANISM Hypocrea jecorina Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea. REFERENCE 1 (bases 1 to 4494) AUTHORS Valkonen,M., Penttila,M. and Saloheimo,M. TITLE The ire1 and ptc2 genes involved in the unfolded protein response pathway in the filamentous fungus Trichoderma reesei JOURNAL Mol. Genet. Genomics 272 (4), 443-451 (2004) PUBMED 15480788 REFERENCE 2 (bases 1 to 4494) AUTHORS Valkonen,M., Penttila,M. and Saloheimo,M. TITLE Direct Submission JOURNAL Submitted (23-JUN-2003) Biotechnology, VTT, Tietotie 2, Espoo 02044-VTT, Finland FEATURES Location/Qualifiers source 1..4494 /organism="Hypocrea jecorina" /mol_type="mRNA" /db_xref="taxon:51453" /note="anamorph: Trichoderma reesei" CDS 510..4241 /note="ER transmembrane receptor in the unfolded protein response" /codon_start=1 /product="serine/threonine kinase IREI" /protein_id="AAP92915.1" /db_xref="GI:33087516" /translation="MMRRPPSQGRWSASHQKLLLAFAFILIPWLQLADAQQQPQQPQI RIHSQRGDAPLDKVADDANTRWYATHAAPDVHPEAKFDTVNRKQKQQSTASPQQHQKY RRAPYDYASKDKAQNRYAQHPIRESEKPNYVKVPNDASALATLAPAQPVRAPHTSRHH WPSSSAASGLASPQNARSLEDWEVEDFVLLATVDGDLYASDRKTGRHLWHLEVDQPVV ETKHYRTNNSVLDDDYRPVDHYIWAVEPSRDGGLYVWIPDSGAGLVRTGFTMKHLVEE LAPYAGDEPPVVYTGDKKTTMVTLDAATGRVLKWFGSSGSQVNEAESCLRPNAFDDRD TTECSSMGTITLGRTEYTVGIQRRDGRPIATLKYAEWGPNTFDSDLYQQYHASLDNHY ITSQHDGRIYAFDKSQAENDLPLYTHKFSSPVARVFDVCRPWDANAGSNPELVVLPQP PIPALDESTVKMRSNSIFLNQTESGDWYALSGRAYPLILDAPVAQISRDDLWDMAHAF DSINPNKLSKALVGTHFLNPVKSTGYHQPPTLPAGALDEYYEDLENASNNAHAVTNTV PEEPTIITKVKALPQSAANSVIDFVSNPILIIFLIGSLIYNEKKLRRSYHRFRTHGTI KDVYPFFVIESEAGDESGDDKDGVFPSSPSPRSQPQDQNAEDHLSRHKVERNAGDQDK VKDNRSLHDVSDTLEPSNKTVEKTADVVKQVDVAGPDAPSTDSNGAAPEKKKKAHRGR RGGVKHRKGRPTDGSQSHENDPALTTVDEAVSNAKKLGDRPSLEPDVMTIYNDMQAVT GSVISMGNIEVDTDVELGMGSNGTVVFAGRFDGRDVAVKRMTIQFYDIATRETKLLRE SDDHPNVIRYYSQVQRGDFLYIALERCAASLADVIEKPYAFGELAKAGQKDLPGVLYQ ITNGISHLHSLRIVHRDLKPQNILVNLDKDGRPRLLVSDFGLCKKLEDRQSSFGATTG RAAGTSGWRAPELLLDDDGQNPAAIDSSTHSGSHTILVGDPNSLSNGGRATRAIDIFS LGLVFFYVLTNGSHPFDCGDRYMREVNIRKGNYNLDPLDALGDFAYEAKDLIASMLQA SPKARPDSREVMAHPFFWSPKKRLAFLCDVSDSLEKEVRDPPSPALVELERHAPEVIK GDFLKVLTRDFVESLGKQRKYTGNKLLDLLRALRNKRNHYEDMSDSLKRSVGSLPDGY LAYWTVKFPMLLLTCWNVVYNLEWEKTDRFREYYEPAGL" ORIGIN 1 gcacgagcaa gatacggcct ctcgcaccaa ggagacacgc atattcgtgg taccatcggc 61 tgagggtgaa ggggggttca acacagcaca actcagcgac cactggactg gtggagccga 121 agcccacgat cgaatccaca gcctgcacca ctttctcctc gtcatattcg cggggactca 181 caagcggttt ccgttgcctt cgaattcgac agagctgcga ctgcgagtca tttcagcgac 241 tctaaaccta ctcctttggc tgctgcgcgg gactggttct gcccagcctc tcctactcga 301 ccaaccgacg tcctctttct gcttcctcat ccctttctcc tttgacgtcc gagcgtcaga 361 gcgaattttt ccttgcttct tcgtttgggc cgggaatggc ttctctggca tcgcaacagc 421 ctctacctct ccgttggtag agccatagcc tgcagctccc catgtgatcc gctctccgtc 481 tctccggcac cccgactttc gtctcgatca tgatgcggcg acccccgagc caaggacgat 541 ggtccgcgtc gcatcagaag ctcctcctgg cttttgcctt tattctcata ccatggctcc 601 aacttgccga tgctcagcag cagcctcagc agccccagat tcgaattcac tcacaaagag 661 gcgacgcgcc ccttgacaaa gtcgccgacg atgccaacac ccgttggtac gcaacacatg 721 ctgcaccaga cgtgcacccc gaagcgaagt tcgacaccgt caacaggaag caaaagcagc 781 agtcgaccgc ttcgccccag caacaccaga aatatcgacg agccccctat gactacgcca 841 gcaaggacaa ggcccagaac cgatatgcgc agcaccctat ccgcgaatcc gagaaaccaa 901 actacgtaaa agtccccaac gatgcgagcg ccctcgcaac tttagctccg gctcagcccg 961 tccgagcacc acacacctca cgacatcact ggcccagcag cagcgccgct tctgggctgg 1021 cctcgccgca gaatgcgcgg agtctggagg actgggaagt tgaagacttt gttcttctgg 1081 cgaccgtcga tggagacctc tatgccagcg accgaaagac cggtcggcac ctctggcacc 1141 tcgaggtcga ccagccagtg gttgaaacca aacactaccg aacaaacaac tccgtcctcg 1201 acgacgacta tcgccccgtc gaccactaca tctgggccgt cgagccgagc cgcgatggag 1261 ggctctatgt atggatcccc gactccggag cgggcctcgt caggaccggc ttcaccatga 1321 agcacctcgt tgaagaactt gctccatacg ccggcgacga gccccccgtt gtctataccg 1381 gagacaagaa gacgaccatg gtcaccctgg acgccgctac cgggcgcgtt ctcaaatggt 1441 ttggctctag cggctcccaa gtcaacgaag ccgagagctg ccttcggccc aatgcctttg 1501 acgacaggga taccacagag tgcagctcca tgggcacaat cacgctggga aggaccgagt 1561 acacggtggg catccagagg cgagacggtc gccctatcgc aaccttgaag tacgcagaat 1621 ggggacccaa cacctttgac agcgacctct accagcaata ccacgcctcg ttggacaacc 1681 attacatcac cagtcagcac gacgggagaa tttacgcgtt tgacaagtca caggcagaaa 1741 acgacctgcc cctctacacc cacaagtttt cgtctcccgt cgcccgggtc ttcgatgtct 1801 gtcgaccgtg ggatgcgaat gcgggaagca acccggagct ggtggttctc ccccaacctc 1861 caattccagc gcttgatgag agcactgtca agatgcgaag caacagcatc ttcctcaacc 1921 agactgaaag cggcgactgg tatgcgctct ccggccgtgc gtatccgctt atactcgatg 1981 cccccgtggc ccagatctcg cgggacgact tgtgggatat ggcccatgcc tttgattcca 2041 ttaacccaaa taagctgtcc aaggccctgg tgggaaccca ctttctgaat cccgtcaaga 2101 gcaccggtta ccatcagccg ccgacgctcc ctgccggcgc cctcgacgag tattacgagg 2161 acttggagaa cgcctcaaac aatgctcacg ccgtgacaaa cactgttccg gaggagccca 2221 ccatcatcac caaagtcaag gctcttccgc agagtgctgc gaacagcgtc attgactttg 2281 tcagcaaccc cattctcatc attttcttga taggctcctt gatctacaac gaaaagaagc 2341 tgcgacggtc gtatcatcgg ttccggactc atggcacaat caaggacgtc tatcccttct 2401 tcgttatcga atctgaggcc ggagatgaat caggtgatga caaggacggt gtgttcccat 2461 cttcgccgtc tccgcgcagt caaccccagg accaaaatgc ggaagaccac ctgtccagac 2521 acaaggtgga gaggaatgcc ggcgaccagg acaaggtcaa ggacaacagg agcctgcatg 2581 acgtttctga caccttggaa ccgagcaaca agactgttga gaaaacggcc gatgtggtca 2641 agcaagtgga tgtagctggc cctgacgcac cctcgacgga ctccaatggt gctgcaccgg 2701 agaagaagaa gaaggctcac cgaggccgtc gtggcggtgt caagcacaga aagggtcggc 2761 ccaccgacgg ctcgcagtct catgaaaacg acccagctct cactacagtg gacgaggctg 2821 taagcaatgc gaagaagctg ggtgaccggc caagcctgga acccgacgtc atgaccatct 2881 acaacgacat gcaagccgtc acgggctctg ttatcagcat gggaaacatc gaggtcgata 2941 cggatgtcga gcttggcatg ggcagcaacg gtactgtcgt atttgctggc cgattcgatg 3001 gcagggacgt cgccgtcaag agaatgacga ttcagttcta cgacattgcc acgcgagaaa 3061 ctaagttgct gcgcgagagt gacgaccacc ccaatgtcat tcggtattac tcacaagtgc 3121 agcgaggcga cttcctgtat attgccttgg aacgctgcgc tgcttcattg gcagatgtca 3181 ttgaaaagcc gtatgccttt ggtgaattgg ccaaggctgg acaaaaggac ctaccgggcg 3241 tcttgtacca aatcaccaac ggcatcagcc acttgcactc tctgcggatt gttcatcgag 3301 acttgaagcc tcaaaacatc ttggtcaact tggacaagga cggcagacca aggctcttgg 3361 tgtcggactt tggcctgtgt aagaaactgg aggatagaca gtcttcgttc ggagcaacga 3421 caggccgagc cgctggaacg tcgggatggc gtgcccccga actgcttctc gatgacgacg 3481 gacagaatcc cgcagccatc gatagcagta cgcacagcgg ctctcacacc atcctcgtgg 3541 gagaccccaa ctcgctttcc aatggagggc gagccacgag ggccattgac atcttctccc 3601 ttggccttgt cttcttctac gtgctcacca atggatccca cccgtttgac tgtggcgaca 3661 gatatatgcg ggaggtgaac attcgaaagg gcaactacaa tctcgatcca ttggacgctc 3721 tgggcgactt tgcctacgaa gccaaggatc tgattgcgtc catgctccag gcctctccca 3781 aggcacgacc cgactcgcga gaggtcatgg cccacccttt cttctggtct ccgaagaagc 3841 gtctggcctt tttgtgcgac gtgtcggatt ctctggagaa ggaggtgcga gatcctccgt 3901 cgcctgcctt ggtcgagctg gagcgacatg cgccggaggt cattaaggga gacttcttga 3961 aggtgctcac gcgcgacttt gtcgagtcgc tgggcaagca gcgcaagtac accgggaaca 4021 agctgctcga cctgttgcgc gctcttcgca acaagcggaa tcactacgaa gacatgtcgg 4081 actcgctgaa gcgcagcgtg ggatcactgc ctgatgggta tcttgcttat tggacggtca 4141 agttcccgat gctgttgctg acgtgctgga acgtggtgta taatctcgag tgggagaaga 4201 cggatcggtt cagggagtac tatgagcctg ccggattgta gaagaaagaa aaggaagaga 4261 aaagaaaggc ctcttgcttg tttggttgct gtatatcttt ttgctcgaag atggaaacgg 4321 aaaatattgg ggaagttgca tgggaagtga acaaaagagg ggaaaaatgg tgaatgtgaa 4381 agcaaagtcg gttagcgggt gggcatggtc gtcatccatg taattgtttc agcttctgtt 4441 gcatcaaaag cgttgtgttt tcgttcttta aaaaaaaaaa aaaaaaaaaa aaaa //