ID   PGK_TRIRE      STANDARD;      PRT;   416 AA.
AC   P14228;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   18-APR-2006, entry version 36.
DE   Phosphoglycerate kinase (EC 2.7.2.3).
GN   Name=pgk1; Synonyms=pgk;
OS   Trichoderma reesei (Hypocrea jecorina).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=QM9414 / Rut C-30;
RX   MEDLINE=89354667; PubMed=2670282;
RA   Vanhanen S., Penttilae M., Lehtovaara P., Knowles J.K.C.;
RT   "Isolation and characterization of the 3-phosphoglycerate kinase gene
RT   (pgk) from the filamentous fungus Trichoderma reesei.";
RL   Curr. Genet. 15:181-186(1989).
CC   -!- CATALYTIC ACTIVITY: ATP + 3-phospho-D-glycerate = ADP + 3-phospho-
CC       D-glyceroyl phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from
CC       D-glyceraldehyde 3-phosphate: step 2.
CC   -!- SUBUNIT: Monomer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the phosphoglycerate kinase family.
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DR   EMBL; X15764; CAA33770.1; -; Genomic_DNA.
DR   PIR; S07803; TVTQGR.
DR   HSSP; P00560; 1QPG.
DR   InterPro; IPR001576; PGK.
DR   Pfam; PF00162; PGK; 1.
DR   PIRSF; PIRSF000724; Pgk; 1.
DR   PRINTS; PR00477; PHGLYCKINASE.
DR   PROSITE; PS00111; PGLYCERATE_KINASE; 1.
KW   ATP-binding; Glycolysis; Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    416       Phosphoglycerate kinase.
FT                                /FTId=PRO_0000145890.
FT   NP_BIND     372    375       ATP (By similarity).
FT   REGION       24     26       Substrate binding (By similarity).
FT   REGION       64     67       Substrate binding (By similarity).
FT   BINDING      40     40       Substrate (By similarity).
FT   BINDING     123    123       Substrate (By similarity).
FT   BINDING     171    171       Substrate (By similarity).
FT   BINDING     220    220       ATP (By similarity).
FT   BINDING     312    312       ATP; via carbonyl oxygen (By similarity).
FT   BINDING     343    343       ATP (By similarity).
SQ   SEQUENCE   416 AA;  44406 MW;  72195841EAB7A4D7 CRC64;
     MSLSNKLSIT DVDLKGKRVL IRVDFNVPLD ENKKITNNQR IVGAIPTIKH ALDNGAKAVV
     LMSHLGRPNG AVNPKYSLKP VVPELERLLG KPVTFARDCV GPEVESIVND ADNGAVILLE
     NLRFHIEEEG SAKDKDGNKT KADKAKVEEF RKGLTALGDI YINDAFGTAH RAHSSMVGVD
     LPQKAAGFLM KKELDYFAKA LESPQRPFLA ILGGAKVSDK IQLIDNLLDK VDTLIVCGGM
     AFTFKKVLNN IPIGTSLFDE AGAKTCPSCR EAKAKNVKLV LPVDYITADK FDKDANTGTA
     TDESGIPDGW MGLDCGEKSI ELYKEAIADA KTILWNGPAG VFEFDKFANG TKATLDAVVE
     GCKNGKIVII GGGDTATVAA KYGVEDKLSH VSTGGGASLE LLEGKELPGV VALSSK
//