ID   GUN5_TRIRE     STANDARD;      PRT;   242 AA.
AC   P43317;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   04-APR-2006, entry version 44.
DE   Endoglucanase-5 precursor (EC 3.2.1.4) (Endoglucanase V)
DE   (Endo-1,4-beta-glucanase V) (Cellulase V) (EG V).
GN   Name=egl5;
OS   Trichoderma reesei (Hypocrea jecorina).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=QM9414 / Rut C-30;
RX   MEDLINE=95075308; PubMed=7984103;
RA   Saloheimo A., Henrissat B., Hoffren A.-M., Teleman O., Penttilae M.;
RT   "A novel, small endoglucanase gene, egl5, from Trichoderma reesei
RT   isolated by expression in yeast.";
RL   Mol. Microbiol. 13:219-228(1994).
CC   -!- CATALYTIC ACTIVITY: Endohydrolysis of 1,4-beta-D-glucosidic
CC       linkages in cellulose, lichenin and cereal beta-D-glucans.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 45 (cellulase K)
CC       family.
CC   -!- SIMILARITY: Contains 1 CBM1 (fungal-type carbohydrate-binding)
CC       domain.
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DR   EMBL; Z33381; CAA83846.1; -; Genomic_DNA.
DR   PIR; S60143; S60143.
DR   HSSP; P00725; 2CBH.
DR   InterPro; IPR009009; Barwin_like.
DR   InterPro; IPR000254; CBD_fun.
DR   InterPro; IPR007112; Expan_endogl.
DR   InterPro; IPR000334; Glyco_hydro_45.
DR   Pfam; PF00734; CBM_1; 1.
DR   Pfam; PF02015; Glyco_hydro_45; 1.
DR   ProDom; PD001821; CBD_fungal; 1.
DR   SMART; SM00236; fCBD; 1.
DR   PROSITE; PS00562; CBM1_1; 1.
DR   PROSITE; PS51164; CBM1_2; 1.
DR   PROSITE; PS50842; EXPANSIN_EG45; 1.
DR   PROSITE; PS01140; GLYCOSYL_HYDROL_F45; 1.
KW   Carbohydrate metabolism; Cellulose degradation; Glycoprotein;
KW   Glycosidase; Hydrolase; Polysaccharide degradation; Signal.
FT   SIGNAL        1     17       Potential.
FT   CHAIN        18    242       Endoglucanase-5.
FT                                /FTId=PRO_0000008022.
FT   DOMAIN      205    241       CBM1.
FT   REGION       18    182       Catalytic.
FT   COMPBIAS    183    205       Pro/Ser-rich (linker).
FT   ACT_SITE     27     27       Nucleophile (By similarity).
FT   ACT_SITE    134    134       Proton donor (By similarity).
FT   CARBOHYD    182    182       N-linked (GlcNAc...) (Potential).
FT   DISULFID    213    230       By similarity.
FT   DISULFID    224    240       By similarity.
SQ   SEQUENCE   242 AA;  24411 MW;  CC033FC51326C71D CRC64;
     MKATLVLGSL IVGAVSAYKA TTTRYYDGQE GACGCGSSSG AFPWQLGIGN GVYTAAGSQA
     LFDTAGASWC GAGCGKCYQL TSTGQAPCSS CGTGGAAGQS IIVMVTNLCP NNGNAQWCPV
     VGGTNQYGYS YHFDIMAQNE IFGDNVVVDF EPIACPGQAA SDWGTCLCVG QQETDPTPVL
     GNDTGSTPPG SSPPATSSSP PSGGGQQTLY GQCGGAGWTG PTTCQAPGTC KVQNQWYSQC
     LP
//