ID   KAPR_TRIAT     STANDARD;      PRT;   462 AA.
AC   Q86ZN7;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   07-FEB-2006, entry version 17.
DE   cAMP-dependent protein kinase regulatory subunit (PKA regulatory
DE   subunit).
GN   Name=pkar1;
OS   Trichoderma atroviride.
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; mitosporic Hypocreales; Trichoderma.
OX   NCBI_TaxID=63577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Zeilinger S., Kubicek C.;
RT   "Trichoderma atroviride cAMP-dependent protein kinase regulatory
RT   subunit.";
RL   Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Tetramer, composed of 2 regulatory (R) and 2 catalytic
CC       (C) subunits. In the presence of cAMP it dissociates into 2 active
CC       monomeric C subunits and an R dimer (By similarity).
CC   -!- SIMILARITY: Belongs to the cAMP-dependent kinase regulatory chain
CC       family.
CC   -!- SIMILARITY: Contains 2 cyclic nucleotide-binding domains.
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DR   EMBL; AF473578; AAO33461.1; -; Genomic_DNA.
DR   HSSP; P12369; 1CX4.
DR   InterPro; IPR002373; cAMP_kin.
DR   InterPro; IPR000595; cNMP_bd.
DR   InterPro; IPR012198; PK_regulatory.
DR   InterPro; IPR003117; RIIa.
DR   Pfam; PF00027; cNMP_binding; 2.
DR   Pfam; PF02197; RIIa; 1.
DR   PIRSF; PIRSF000548; PK_regulatory; 1.
DR   PRINTS; PR00103; CAMPKINASE.
DR   SMART; SM00100; cNMP; 2.
DR   PROSITE; PS00888; CNMP_BINDING_1; 2.
DR   PROSITE; PS00889; CNMP_BINDING_2; 2.
DR   PROSITE; PS50042; CNMP_BINDING_3; 2.
KW   cAMP; cAMP-binding; Nucleotide-binding; Phosphorylation; Repeat.
FT   CHAIN         1    462       cAMP-dependent protein kinase regulatory
FT                                subunit.
FT                                /FTId=PRO_0000205415.
FT   NP_BIND     204    333       cAMP 1.
FT   NP_BIND     336    453       cAMP 2.
FT   REGION       54    203       Dimerization and phosphorylation
FT                                (Potential).
FT   BINDING     282    282       cAMP 1 (By similarity).
FT   BINDING     291    291       cAMP 1 (By similarity).
FT   BINDING     401    401       cAMP 2 (By similarity).
FT   BINDING     410    410       cAMP 2 (By similarity).
FT   MOD_RES     164    164       Phosphoserine (By similarity).
SQ   SEQUENCE   462 AA;  50151 MW;  8281DDE474ABA145 CRC64;
     MSLPEAYQLE IQALNKQVLQ TCPSDILQFC ADFFNSRLAT ERAASISLFR DRGTPSPRFP
     PSPTNPHFGM MSSQFSSPFG ANANPFGGSS SNPNPFGGSA SPMSSSVMHR VVEEDESDNH
     LAPGGSLFSG AFGGDASTEA PPTLRAPPTT DSYPAQYNFS RRTSVSAESL KPSADGFDNW
     TPPYTDKTPE QVERLKYAIE GNFLFSHLDD EQSAQILGAL VEKPIPARGI KVISQGDAGD
     YFYVVERGSF DVYVNDCGFI EPGPDGLGNK VGTIQAGGSF GELALMYNAP RAATIISAEG
     SCTLWALDRV TFRRILMEST FARRRMYENF LEEVPILSSL TPYERSKISD ALETQKFAPG
     DVIIHEGDPG HSFYLLESGE AAAFKGEEQV LSYKKGDFFG ELALLNDAPR AASVIATSDV
     KVATLGKNAF QRLLGPVEGL LRRTRYLGVK TGVEEMDPLH TQ
//