ID   GAL7_TRIRE     STANDARD;      PRT;   382 AA.
AC   Q96UI1;
DT   30-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   07-FEB-2006, entry version 29.
DE   Galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) (Gal-1-P
DE   uridylyltransferase) (UDP-glucose--hexose-1-phosphate
DE   uridylyltransferase).
GN   Name=gal7;
OS   Trichoderma reesei (Hypocrea jecorina).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=QM9414 / Rut C-30;
RA   Seiboth B., Hofmann G., Kubicek C.P.;
RT   "Lactose metabolism and cellulase production in Hypocrea jecorina: the
RT   gal7 (galactose-1-phosphate uridylyltransferase) gene is essential for
RT   growth on galactose but not for cellulase induction.";
RL   Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: UDP-glucose + alpha-D-galactose 1-phosphate =
CC       alpha-D-glucose 1-phosphate + UDP-galactose.
CC   -!- COFACTOR: Binds 1 iron ion per subunit (Potential).
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (Potential).
CC   -!- PATHWAY: Galactose metabolism; second step.
CC   -!- SIMILARITY: Belongs to the galactose-1-phosphate
CC       uridylyltransferase type 1 family.
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DR   EMBL; AY057108; AAL14201.1; -; Genomic_DNA.
DR   HSSP; P09148; 1HXQ.
DR   InterPro; IPR001937; GalP_UDPtransf1.
DR   InterPro; IPR011573; GalP_Utransf.
DR   InterPro; IPR005850; GalP_Utransf_C.
DR   InterPro; IPR005849; GalP_Utransf_N.
DR   PANTHER; PTHR11943; GalP_Utransf; 2.
DR   Pfam; PF02744; GalP_UDP_tr_C; 1.
DR   Pfam; PF01087; GalP_UDP_transf; 1.
DR   PIRSF; PIRSF000808; GalT; 1.
DR   ProDom; PD005051; GalP_Utransf; 2.
DR   TIGRFAMs; TIGR00209; galT_1; 1.
DR   PROSITE; PS00117; GAL_P_UDP_TRANSF_I; 1.
KW   Carbohydrate metabolism; Galactose metabolism; Iron; Metal-binding;
KW   Nucleotidyltransferase; Transferase; Zinc.
FT   CHAIN         1    382       Galactose-1-phosphate
FT                                uridylyltransferase.
FT                                /FTId=PRO_0000169892.
FT   ACT_SITE    198    198       Tele-UMP-histidine intermediate (By
FT                                similarity).
FT   METAL        55     55       Zinc (Potential).
FT   METAL       196    196       Zinc (Potential).
FT   METAL       214    214       Iron (Potential).
FT   METAL       313    313       Iron (Potential).
FT   METAL       330    330       Iron (Potential).
FT   METAL       332    332       Iron (Potential).
SQ   SEQUENCE   382 AA;  43781 MW;  25A08CC695C39794 CRC64;
     MPDKILDDIS HRRYNPLTDS WLLVSPHRTK RPWQGQQEGA AVTTLPEYDP KCYLCPGNSR
     AAGDQNPNYE QTFAFVNDYS AVKEQQPDYE VDQSSDDLES LLLRAQGVKG VCYVLTFSPK
     HNVTLADMSA KDILPTINHW TRLYANHLSP SNPLSAVAAQ LQLPISKEEA PVPKDNYRYM
     QIFENKGAAM GCSNPHPHCQ AWTTSTMPEE PGKELVQMAK YRQQHGRHLL ADYIKLELAK
     EERVVWQNDS FVVVCPWWAI WPFEVLVLPK RHVRALVDLT ADERLQLAEA IQEVTRRYDN
     LFECHFPYSS GIHQAPLDGT PEEIENAYFH MHFYPPLLRS ATVKKFLVGF ELMAEAQRDI
     TPEQATIRLR ACDGELYRNK LS
//