ID   ACE2_TRIRE     STANDARD;      PRT;   341 AA.
AC   Q96WN6;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   07-FEB-2006, entry version 19.
DE   Transcription factor ACEII.
GN   Name=ace2;
OS   Trichoderma reesei (Hypocrea jecorina).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=QM9414 / Rut C-30;
RX   MEDLINE=21316469; PubMed=11304525; DOI=10.1074/jbc.M003624200;
RA   Aro N., Saloheimo A., Ilmen M., Penttilae M.;
RT   "ACEII, a novel transcriptional activator involved in regulation of
RT   cellulase and xylanase genes of Trichoderma reesei.";
RL   J. Biol. Chem. 276:24309-24314(2001).
CC   -!- FUNCTION: Positive regulation of the major cellulase and xylanase
CC       genes (cbh1, cbh2, egl2 and xyn2). Binds to the 5'-GGCTAATAA-3'
CC       site present in the cbh1 promoter.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Probable).
CC   -!- SIMILARITY: Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.
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DR   EMBL; AF220671; AAK69383.1; -; Genomic_DNA.
DR   HSSP; P07272; 1PYI.
DR   GO; GO:0005634; C:nucleus; IC.
DR   GO; GO:0003700; F:transcription factor activity; IDA.
DR   GO; GO:0016563; F:transcriptional activator activity; IDA.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-d...; IDA.
DR   InterPro; IPR001138; Fungi_Trscrp_N.
DR   Pfam; PF00172; Zn_clus; 1.
DR   PRINTS; PR00054; FUNGALZNCYS.
DR   SMART; SM00066; GAL4; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
KW   Activator; DNA-binding; Metal-binding; Nuclear protein; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN         1    341       Transcription factor ACEII.
FT                                /FTId=PRO_0000114929.
FT   DNA_BIND      7     36       Zn(2)-C6 fungal-type.
FT   COMPBIAS     48     65       His-rich.
SQ   SEQUENCE   341 AA;  37725 MW;  190F68D4571F92F5 CRC64;
     MDLRQACDRC HDKKLRCPRI SGSPCCSRCA KANVACVFSP PSRPFRPHEP LNHSHEHSHS
     HSHNHNGVGV SFDWLDLMSL EQQQEQQQGQ PQHPPPPVQT LSERLAALLC ALDRMLQAVP
     SSLDMHHVSR QQLREYADTV GTGFDLQSTL DSLLHHAQDL ASLYSEAVPA SFNKRTTAAE
     ADALCAVPDC VHQDRTSLHT TPLPKLDHAL LNLVMACHIR LLDVMDTLAE HGRMCAFMVA
     TLPPDYDPKF AVPEIRVGTF VAPTDTAASM LLSVVVELQT VLVARVKDLV AMVDQVKDDA
     RAAREAKVVR LQCGILLERA ESTLGEWSRF KDGLVSARLL K
//