ID   AGUA_TRIRE     STANDARD;      PRT;   847 AA.
AC   Q99024;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   07-FEB-2006, entry version 34.
DE   Alpha-glucuronidase precursor (EC 3.2.1.139) (Alpha-glucosiduronase)
DE   (GLRI).
OS   Trichoderma reesei (Hypocrea jecorina).
OC   Eukaryota; Fungi; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Hypocrea.
OX   NCBI_TaxID=51453;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=QM9414 / Rut C-30;
RX   MEDLINE=96257277; PubMed=8654984; DOI=10.1016/0378-1119(96)00167-9;
RA   Margolles-Clark E., Saloheimo M., Siika-Aho M., Penttilae M.;
RT   "The alpha-glucuronidase-encoding gene of Trichoderma reesei.";
RL   Gene 172:171-172(1996).
CC   -!- FUNCTION: Releases 4-O-methylglucuronic acid from xylan.
CC   -!- CATALYTIC ACTIVITY: An alpha-D-glucuronoside + H(2)O = an alcohol
CC       + D-glucuronate.
CC   -!- SUBCELLULAR LOCATION: Secreted protein.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 67 family.
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DR   EMBL; Z68706; CAA92949.1; -; mRNA.
DR   PIR; JC4836; JC4836.
DR   HSSP; Q8VVD2; 1L8N.
DR   InterPro; IPR011395; Alpha-glucuronds.
DR   InterPro; IPR005154; Glyco_hydro_67.
DR   InterPro; IPR011099; Glyco_hydro_67C.
DR   InterPro; IPR011100; Glyco_hydro_67M.
DR   Pfam; PF07477; Glyco_hydro_67C; 1.
DR   Pfam; PF07488; Glyco_hydro_67M; 1.
DR   Pfam; PF03648; Glyco_hydro_67N; 1.
DR   PIRSF; PIRSF029900; Alpha-glucuronds; 1.
KW   Direct protein sequencing; Glycoprotein; Glycosidase; Hydrolase;
KW   Signal; Xylan degradation.
FT   SIGNAL        1     19       Potential.
FT   CHAIN        20    847       Alpha-glucuronidase.
FT                                /FTId=PRO_0000012244.
FT   CARBOHYD     52     52       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    238    238       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    321    321       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    353    353       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    586    586       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    692    692       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    740    740       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    767    767       N-linked (GlcNAc...) (Potential).
SQ   SEQUENCE   847 AA;  93424 MW;  214AAE487382FDB4 CRC64;
     MVIRSLLLLL LAAIVPVFAE SGIDAWLRYA RLPSSATRGH LTSFPDRIVV LNASKNGPLA
     SASSELHKGI KGILGLDLDV SSRGGKHCST QKSIVISTLD TYQSACGKLS PKLNLKEDGY
     WLSTKGGSVQ IIGQNERGAL YGAFQYLSYL GQGDFSGKAF ASNPSAPVRW SNQWDNLNAA
     TAAHGSIERG YGGPSIFFEN GLIKEDLSRV PLYGRLLASV GLNGIVINNV NADANLLNET
     NLQGLKRIAD LFRPWGVNVG ISLNFASPQV LGDLSTFDPL DDSVIKWWTD KTDRIYQLVP
     DLAGYLVKAN SEGQPGPLTY NRTLAEGANL FAKAVQPHGG IVVFRAFVYD QLNETDWKAD
     RANAAVDFFK SLDGQFDDNV LVQIKYGPID FQVREPASPL FANLPKTAVS IELEVTQEYL
     GQQSHLVYLP PLWQTVLGFD MRYNNRQSYV RDIISGEVFG HKLGGYAGVI NVGMDDTWLG
     SHLAMSNMFA YGRLAWNPRA DSRDIVEEWT RLTFGLDRDV VSTIADMSLK SWPAYEGYSG
     NLGIQTLTDI LYTHYGANPA SQDNNGWGQW TRADSKTIGM DRTVSNGTGN AGQYPKEVAA
     RFEHTQTTPD DLMLWFHHVP YTFRLHSGKS VIQHFYDAHY TGAATVQRFP AAWKSLKSKI
     DTERYNAVLY KLQYQTGHSL VWRDAITEFY RNLSSIPDQL NRVRNHPHRI EAEDMDLSGF
     TVVNVSPTEC ASKYKAIATN GTGTATTRLN VPSGKYTVAV NYYDVINGTA SYDVLLNGKS
     LGKWKGDSET HLGHDFSTFL DCHSAIRITF EGVRISRGDK LTIRGTGNAQ EQAAIDYVSI
     LPQGVVD
//