LOCUS       Q9KJU0                   264 aa            linear   BCT 28-NOV-2006
DEFINITION  Protein grpE (HSP-70 cofactor).
ACCESSION   Q9KJU0
VERSION     Q9KJU0  GI:52782981
DBSOURCE    swissprot: locus GRPE_PEWBP, accession Q9KJU0;
            class: standard.
            created: Sep 27, 2004.
            sequence updated: Oct 1, 2000.
            annotation updated: Nov 28, 2006.
            xrefs: AF160726.1, AAF89528.1
            xrefs (non-sequence databases): GO:0030189, HAMAP:MF_01151,
            InterPro:IPR000740, InterPro:IPR013805, InterPro:IPR009012,
            Gene3D:G3DSA:2.30.22.10, Pfam:PF01025, PRINTS:PR00773,
            PROSITE:PS01071
KEYWORDS    Chaperone; Heat shock.
SOURCE      Peanut witches'-broom phytoplasma
  ORGANISM  Peanut witches'-broom phytoplasma
            Bacteria; Firmicutes; Mollicutes; Acholeplasmatales;
            Acholeplasmataceae; Candidatus Phytoplasma; 16SrII (Peanut WB
            group).
REFERENCE   1  (residues 1 to 264)
  AUTHORS   Chu,P.W. and Lin,C.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (??-JUN-1999)
  REMARK    NUCLEOTIDE SEQUENCE [GENOMIC DNA].
COMMENT     [FUNCTION] Participates actively in the response to hyperosmotic
            and heat shock by preventing the aggregation of stress-denatured
            proteins, in association with dnaK and grpE. It is the nucleotide
            exchange factor for dnaK and may function as a thermosensor.
            Unfolded proteins bind initially to dnaJ; upon interaction with the
            dnaJ-bound protein, dnaK hydrolyzes its bound ATP, resulting in the
            formation of a stable complex. GrpE releases ADP from dnaK; ATP
            binding to dnaK triggers the release of the substrate protein, thus
            completing the reaction cycle. Several rounds of ATP-dependent
            interactions between dnaJ, dnaK and grpE are required for fully
            efficient folding (By similarity).
            [SUBUNIT] Homodimer (By similarity).
            [SUBCELLULAR LOCATION] Cytoplasm (Probable).
            [SIMILARITY] Belongs to the grpE family.
FEATURES             Location/Qualifiers
     source          1..264
                     /organism="Peanut witches'-broom phytoplasma"
                     /db_xref="taxon:35772"
     gene            1..264
                     /gene="grpE"
     Protein         1..264
                     /gene="grpE"
                     /product="Protein grpE"
     Region          1..264
                     /gene="grpE"
                     /region_name="Mature chain"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Protein grpE. /FTId=PRO_0000113832."
     Region          74..257
                     /gene="grpE"
                     /region_name="GrpE"
                     /note="Molecular chaperone GrpE (heat shock protein)
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG0576"
                     /db_xref="CDD:30921"
     Region          120..255
                     /gene="grpE"
                     /region_name="GrpE"
                     /note="GrpE is the adenine nucleotide exchange factor of
                     DnaK (Hsp70)-type ATPases; cd00446"
                     /db_xref="CDD:48345"
ORIGIN      
        1 mqefmnfeec skqntnnckq heknidennc sckekkvqsk kvssdhssse dnassdinsn
       61 kaetltlncg dqsdnknsis diesnkfipn endfqmlkkq lndlkaenvn lkrdlqeahq
      121 qrtndnlkyl adfdnfkkri tvqtnreiky altdfiknil ipleqfekvl empkvddsvk
      181 sfllgfkmih kqvkdilqke gveeikalgv kfdpnfhyal ekisdlkqpn ginvlvlqkg
      241 flykdlvikp amvkvnewsd knnd
//